Formulation and evaluation of acne serums

Adarsh Suryavanshi; Naga Subrahmanyam S; Suvarna Jyothi Navuduri

doi:10.37022/tjmdr.v5i2.745

Suryavanshi.Adarsh Ⅳ/Ⅳ B.Pharmacy, Koringa College of Pharmacy, Koringi, Kakinada District, A.P-533461
Naga Subrahmanyam S Professor, Department of Pharmacy Practice, Koringa College of Pharmacy, Koringi, Kakinada District, A.P-533461
Suvarna Jyothi Navuduri Professor and Principal, Koringa College of Pharmacy, Koringi, Kakinada District, A.P-533461

DOI https://doi.org/10.37022/tjmdr.v5i2.745

Abstract

Skin acne is a common skin condition that occurs when hair follicles become clogged with oil and dead skin cells. In this paper, the use tea tree oil, aloe vera, lavender, and calendula for skin acne is reviewed along with a survey of the views of first-year pharmacy students on these products. The survey included 5 knowledge-based and 5 opinion-based questions, focusing on skin acne remedies. The survey enrolled 10 male and 29 female participants. The response rate for the demographic questions was 100%. In the knowledge-based and opinion survey questions, 34 participated for a response rate of about 87%. For the knowledge-based questions, the correct average response rate was 75.9%, with one question scoring 14.7% correct rate. The highest correct response rate was 97.1%. Opinion-based questions revealed a positive attitude towards herbal skin acne remedies with approximately 37.4% expressing strong agreement. On average, over 93% of the respondents agreed with the positive aspects of the products. Nearly 53% strongly believed that lavender has therapeutic properties such as promoting relaxation and reducing stress.

Keywords: Skin acne, Herbal remedies, Tea tree oil, Lavender, Pharmacy students, Survey analysis

References

1. Webster GF. Evidence-based review: fixed-combination therapy and topical retinoids in the treatment of acne. J Drugs Dermatol. 2011;10:636–44.
2. Gollnick H. From new findings in acne pathogenesis to new approaches in treatment. J Eur Acad Dermatol Venereol. 2015;29(Suppl 5):1–7.
3. Melnik B. Dietary intervention in acne: Attenuation of increased mTORC1 signaling promoted by Western diet. Dermatoendocrinol. 2012;4:20–32.
4. Grange PA, Raingeaud J, Calvez V, et al. Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-kappaB and MAPK pathways. J Dermatol Sci. 2009;56:106–12.
5. Lee WR, Kim KH, An HJ, et al. The protective effects of melittin on Propionibacterium acnes-induced inflammatory responses in vitro and in vivo. J Invest Dermatol. 2014;134:1922–30.
6. Han SM, Lee KG, Park KK, et al. Skin sensitization study of bee venom (Apis mellifera L.) in guinea pigs and rats. Cutan Ocul Toxicol. 2013;32:27–30.
7. Bataille V, Snieder H, MacGregor AJ, et al. The influence of genetics and environmental factors in the pathogenesis of acne: a twin study of acne in women. J Invest Dermatol. 2002;119:1317–22.
8. Ismail NH, Manaf ZA, Azizan NZ. High glycemic load diet, milk and ice cream consumption are related to acne vulgaris in Malaysian young adults: a case control study. BMC Dermatol. 2012;12:13.
9. Katzman M, Logan AC. Acne vulgaris: nutritional factors may be influencing psychological sequelae. Med Hypotheses. 2007;69:1080–4.
10. Rollman O, Vahlquist A. Oral isotretinoin (13-cis-retinoic acid) therapy in severe acne: drug and vitamin A concentrations in serum and skin. J Invest Dermatol. 1986;86:384–8.
11. Stéphan F, Revuz J. Zinc salts in dermatology. Ann Dermatol Venereol. 2004;131:455–60.
12. Vahlquist A, Michaëlsson G, Juhlin L. Acne treatment with oral zinc and vitamin A: effects on the serum levels of zinc and retinol binding protein (RBP). Acta Derm Venereol. 1978;58:437–42.
13. Michaëlsson G, Juhlin L, Vahlquist A. Effects of oral zinc and vitamin A in acne. Arch Dermatol. 1977;113:31–1.
14. Doshi A, Zaheer A, Stiller MJ. A comparison of current acne grading systems and proposal of a new system. Int J Dermatol. 1997;36:416–8.
15. Gerald F. Considering the individual vitamins. In: The vitamins fundamental aspects in nutrition and health. 2nd ed. New York: Academic Press; 1998. p. 105–223.
16. Di Mascio P, Murphy ME, Sies H. Antioxidant defense system: the role of carotenoids, tocopherols, and thiols. Am J Clin Nutr. 1991;53:194–200.
17. El-Akawi Z, Abdel-Latif N, Abdul-Razzak K. Does the plasma level of vitamins A and E affect acne condition? Clin Exp Dermatol. 2006;31:430–4.
18. Ayres S Jr, Angeles L. Acne vulgaris: correcting pathophysiologic defects versus antibacterial therapy. Int J Dermatol. 1986;5:335.

Formulation and evaluation of acne serums

Abstract

References

Most read articles by the same author(s)