The Journal of Multidisciplinary Research

A study on drug regimen and life style modification of type 1 diabetes mellitus in children and adolescents

Fri, 21 Feb 2025 00:00:00 +0530

Type 1 diabetes mellitus (T1DM) impacts millions of individuals worldwide and necessitates meticulous management to prevent severe long-term complications, such as cardiovascular and renal diseases, stroke, and vision impairment. People with T1DM are very different from one another. They show signs of the disease at different stages and levels of severity, and their genetic backgrounds and disease causes are also very different. This 6-month study focused on patients with T1DM at the paediatrics department of SVS Medical College and Hospital in Mahbubnagar. We collected and evaluated data from one hundred patients. This study underscores the significant impact on individuals aged 11-15 years, and our research findings reveal a higher prevalence of T1DM in males. We also conclude that obesity presents the highest risk of hyperglycaemia. Currently, the standard treatment for T1DM involves exogenous insulin substitution therapy; however, this method does not consistently provide optimal blood glucose control for many individuals. In addition to the appropriate insulin regimen, we also advocate for lifestyle management, which seeks to implement “the right therapy at the right time, for the right patient.” As previously stated, innovative strategies are essential for T1DM prevention and management. We also recommend that physical activities provide multiple benefits for individuals with T1DM. Regular physical activity improves overall well-being, aids in obesity prevention, and reduces cardiovascular risk in patients with type 1 diabetes mellitus.

A review on lung cancer

Tue, 11 Feb 2025 00:00:00 +0530

Lung cancer is a kind of cancer that starts as a growth of cells in the lungs. The lungs are two spongy organs in the chest that control breathing. People who smoke have the greatest risk of lung cancer. The risk of lung cancer increases with the length of time and number of cigarettes smoked. Quitting smoking, even after smoking for many years, significantly lowers the chances of developing lung cancer. Lung cancer also can happen in people who have never smoked. Lung cancer is the prime cause of cancer death among both men and women according to WHO report 2.09 million cases globally. It is also the chief cause of cancer death among men and the second leading cause of cancer death among women worldwide. The lung cancer classified into two different types is small-cell lung cancers (SCLC) and non-small-cell lung cancers (NSCLC). This article focuses on modifiable risk factors, including tobacco smoking, occupational carcinogens, diet, and ionizing radiation. It also discusses briefly the molecular and genetic aspects of lung carcinogenesis. Lung cancer is the most frequent cancer type with high mortality and morbidity rate worldwide. Studies have chemotherapy. own that smoking, environmental factors including occupational exposure, radon exposure, air pollution, radiation, obesity, diet and hereditary susceptibility are related to developing risk of LC.

Hibiscus sabdariffa l.-a review on its pharmacological activity & medicinal uses

Neha Kumari, Amar Pal Singh, Ajeet Pal Singh — Thu, 20 Feb 2025 00:00:00 +0530

The shrub Hibiscus sabdariffa is a member of the Malvacea family. There are more than 200 species of hibiscus in the world. It has been noted that Hisbiscussabdariffa has numerous therapeutic benefits. The calyx is red and has five large sepals, the leaves are 7.5 to 12.5 cm long, and the fruit is a velvety capsule that is 1.25-2 cm long and green in color with five valves that each contain three to four seeds. The entire plant exhibits a wide range of pharmacological properties. The presence of phytochemicals like flavonoids, pectin, antioxidants, anthocyanins, hibiscus acid, vitamin C, protein, citric acid, and β-carotene is primarily responsible for these activities.