FLOATING DRUG DELIVERY SYSTEM CURRENT TRENDS, CHALLEGE AND

Ramanjaneyulu Reddy R

R. Ramanjaneyulu Reddy Priyadarshini Institute of Pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur-522017, Andhra Pradesh, India.

Abstract

The floating drug delivery system FDDS remains buoyant upon contact with gastric fluids, thereby improving the bioavailability of drugs intended for absorption in the upper small intestine. Immediate floating capability is only attainable when the components of the device are characterized by low density in their initial state. This review encompasses both in vitro methodologies and in vivo research investigations that are utilized by researchers to evaluate floating systems. Floating dosage forms can be administered in traditional formats such as tablets and capsules, supplemented with appropriate ingredients and a gas-generating agent. The review elucidates the techniques for creating floating systems, which include evaluation and characterization methods for pharmaceutical dosage forms via FDDS, while also detailing classification systems and all established as well as emerging techniques employed in the development of floating dosage forms. The review elucidates the techniques for creating floating systems, which include evaluation and characterization methods for pharmaceutical dosage forms via FDDS, while also detailing classification systems and all established as well as emerging techniques employed in the development of floating dosage forms.

Keywords: Floating Drug Delivery System, single unit and multiple unit floating system, In vitro and in vivo evaluation, Novel advancements

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