POLYMERIC NANOPARTICLES IN MODERN OPTHALMIC FORMULATION

Anjali Ponugubati

Ponugubati Anjali Priyadarshini Institute of Pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur-522017, Andhra Pradesh, India.

Abstract

Ophthalmic drug delivery presents significant therapeutic challenges due to anatomical and physiological barriers that restrict drug penetration into ocular tissues. Conventional dosage forms such as eye drops and ointments exhibit limited drug retention and rapid precorneal elimination, resulting in poor therapeutic outcomes. Nanotechnology-based delivery systems have emerged as promising approaches to enhance ocular drug bioavailability and therapeutic effectiveness through improved drug penetration and targeted delivery. Nanocarriers including dendrimers, polymeric nanoparticles, and nanofibers enable sustained drug release and protection of therapeutic agents from degradation. Nanomedicine-based systems also provide improved ocular penetration, reduced dosing frequency, and minimized toxicity, thereby enhancing patient compliance.

Keywords: Nano technology, ophthalmic drug delivery, nano carriers, polymeric nanoparticles

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