Pharmacognostic standardization and physicochemical evaluation of Psoralea corylifolia Linn. Seeds

Ria P. Mathew; Darshana Patil; Avinash Patil

doi:10.46796/ijpc.v6i3.691

Ria P. Mathew Department of Botany, B.K. Birla College, Kalyan, Maharashtra, India
Darshana Patil Department of Botany, Smt. C.H.M. College, Ulhasnagar, Maharashtra, India
Avinash Patil Department of Botany, B.K. Birla College, Kalyan, Maharashtra, India

DOI https://doi.org/10.46796/ijpc.v6i3.691

Abstract

Psoralea corylifolia Linn. is a medicinally important herb belonging to the family Fabaceae. The present research work has been carried out on the seed of this plant and is an attempt to establish quality control parameters for Psoralea corylifolia Linn. seeds so that it could be useful in setting some diagnostic parameters for the correct identification, standardization and preparation of monographs. Standardization was carried out in terms of pharmacognostic, physicochemical and preliminary phytochemical analysis and development of an HPTLC fingerprint profile. Preliminary phytochemical analysis indicated presence of various phytoconstituents like acid compounds, aleurone grains, amino acids, carbohydrates, fats and fixed oils, starch, alkaloids, flavonoids, glycosides, steroids and triterpenoids, tannins, resins and saponins.. The HPTLC fingerprint profile developed is unique to Psoralea corylifolia Linn. seed powder. This unique band pattern obtained from HPTLC fingerprint can be used for proper identification and quality control of Psoralea corylifolia Linn. seed. Thus the present study provides referential information for correct identification and standardization of Psoralea corylifolia Linn. seed.

Keywords: Standardization, Pharmacognosy, Monograph, Phytoconstituents, HPTLC fingerprint profile

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References

1. Vidua G, Shrivastava D, Tiwari AK, Bhardwaj S, Tripathi M, Tiwari A. Quality control and pharma-cognostical activity of Psoralea corylifolia Linn. J Chem Pharm Res. 2015;7(6):249–56.
2. Masihuzzaman AM, Iftikhar MY, Alia B, Farheen K. Babchi (Psoralea corylifolia Linn.): An effective Unani medicine for dermatological disorders: A re-view. Int J Unani Integr Med. 2022;6(1):17–21. doi:10.33545/2616454x.2022.v6.i1a.203
3. Alam F, Khan GN, Asad MHHB. Psoralea corylifolia L: Ethnobotanical, biological, and chemical aspects: A review. Phytother Res. 2017;32(4):597–615. doi:10.1002/ptr.6006
4. Ruan B, Kong LY, Takaya Y, Niwa M. Studies on the chemical constituents of Psoralea corylifolia L. J Asian Nat Prod Res. 2005;9(1):41–4.

5. Moteriya P, Padalia H, Rathod T, Desai D, Chanda S. Pharmacognostic standardization of Madhuca in dica leaf and stem, an important medicinal plant. Int J Pharm Sci Res. 2014;6(2):705–11.
6. Chanda S. Importance of pharmacognostic study of medicinal plants: An overview. J Pharmacogn Phytochem. 2014;2(5):69–73.
7. Mukherjee PK. Quality control of herbal drugs: An approach to evaluation of botanicals. New Delhi: Business Horizons Pharmaceutical Publishers; 2005.
8. World Health Organization (WHO). Quality control methods for herbal materials. Geneva: WHO; 2011.
9. Chase CR, Pratt RJ. Fluorescence of powdered vegetable drugs with particular reference to development of a system of identification. J Am Pharm Assoc. 1949;38:324–33.
10. Kokoski CJ, Kokoski RJ, Slama FJ. Fluorescence of powdered vegetable drugs under ultraviolet radiation. J Am Pharm Assoc Sci Ed. 1958;47(10):715–7.
11. Khandelwal KR, Sethi V. Practical Pharmacognosy: Techniques and Experiments. 27th ed. Pune: Nirali Publication; 2016.
12. Kokate CK, Purohit AP, Gokhale SB. Pharmacog-nosy. 42nd ed. Pune: Nirali Publication; 2008.
13. Arya V, Thakur R. Organoleptic and microscopic analysis of Gentiana regeliana. J Pharmacogn Phy-tochem. 2012;1(2):32–5.
14. Akbar S, Hanif U, Ali J, Ishtiaq S. Pharmacognostic studies of stem, roots and leaves of Malva par-viflora L. Asian Pac J Trop Biomed. 2014;4(5):410–5. doi:10.12980/apjtb.4.2014c1107
15. Ranjith D. Fluorescence analysis and extractive values of herbal formulations used for wound healing activity in animals. J Med Plants Stud. 2018;6(2):189–92.
16. Alagar RM, Shailaja V, David B, Rao KNV, Selvaku-mar D. Evaluation of standardisation parameters, pharmacognostic study, preliminary phytochemi-cal screening and in vitro antidiabetic activity of Emblica officinalis fruits as per WHO guidelines. J Pharmacogn Phytochem. 2014;3(4):21–8.
17. Gupta MK. Pharmacognostical evaluation of Grewia asiatica. Int J Plant Sci. 2006;1(2):249–51.
18. Ansari SH. Essentials of Pharmacognosy. 1st ed. New Delhi: Birla Publications Pvt. Ltd; 2006.
19. Kannan NB, Devi GV, John A, Natarajan M, Kanagarajan A. Pharmacognostic evaluation and HPTLC fingerprinting of Pirantai Vatakam, a Siddha formulation. J Phytopharmacol. 2019;8(2):33–7.
20. Silva GOD, Abeysundara AT, Aponso MMW. Extraction methods, qualitative and quantitative techniques for screening of phytochemicals from plants. Am J Essent Oil Nat Prod. 2017;5(2):29–32.
21. Shaikh JR, Patil M. Qualitative tests for preliminary phytochemical screening: An overview. Int J Chem Stud. 2020;8(2):603–8. doi:10.22271/chemi.2020.v8.i2i.8834
22. Mohammed MS, Alajmi MF, Alam P, Khalid HS, Mahmoud AM, Ahmed WJ. Chromatographic fin-gerprint analysis of anti-inflammatory active ex-tract fractions of aerial parts of Tribulus terrestris by HPTLC technique. Asian Pac J Trop Biomed. 2014;4(3):203–8. doi:10.1016/s2221-1691(14)60232-x
23. Yamunadevi M, Wesely EG, Johnson M. Chroma-tographic fingerprint analysis of steroids in Aerva lanata L. by HPTLC technique. Asian Pac J Trop Biomed. 2011;1:428–33.