Leaf extract, phytochemical studies and preparation of herbal formulation justicia adhatoda lehya
Abstract
Leyha, a novel pharmaceutical method of administration through licking, offers unique benefits across various medical fields. This approach, starting with the tongue, emphasizes its importance in drug delivery and therapeutic effectiveness. Particularly notable is the inclusion of vasaka, which shows combined effects in treating multiple conditions. Standardizing Leyha formulations not only aids in understanding its preparation but also opens doors to innovative pharmaceutical techniques. The flexibility of this method presents exciting opportunities for developing medications targeting serious diseases. This summary highlights the diverse potential of Leyha in pharmaceutical innovation, underlining its role in enhancing therapeutic results and expanding the scope of medical treatments.
Keywords:
Leyha, Pharmaceutical mode, Licking, Vasaka, Synergistic effect, Drug delivery
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References
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2. Herbal Pharmacognosy: Kristian Leisegang, in Herbal Medicine in Andrology, 2021. Science direct. Com. Medicine and dentistry pharmacognosy.
3. Background to Pharmacognosy: T. O. Elufioye, S, Badal in Pharmacognosy, 2017.Science direct. Com. Medicine and dentistry pharmacognosy.
4. 4. Semwal DK, Mishra SP, Chauhan A, Semwal RB. Adverse health effects of tobacco and role of Ay-urveda in their reduction. J Med Sci. 2015; 15:139–46
5. Lad V. Ayurveda, the Science of Self-Healing: A Practical Guide. 2nd Ed. New Delhi: Lotus Press; 1987.
6. Jamwal S, Jena MK, Tyagi N, Kancharla S, Kolli P, Mandadapu G, Kumar S, Mohanty AK. Proteomic Ap-proaches to Unravel the Molecular Dynamics of Early Pregnancy in Farm Animals: An In-Depth Review. Journal of Developmental Biology. 2023 Dec 30;12(1):2.
7. Humber JM. The role of complementary and alterna-tive medicine: Accommodating pluralism. J Am Med Assoc. 2002; 288:1655–6.
8. Basisht G. Exploring progression of Ayurveda. Ayu. 2011; 32:445–7.
9. Svoboda R. New Delhi: Penguin Books India; 1992. Ayurveda: Life, Health and Longevity.
10. Tiwari M. Delhi: Motilal Banarsidass Publisher; 2003. Ayurveda: Secrets of Healing.
11. Dahanukar SA, Thatte UM. Bombay: Popular Praka-shan; 1989. Ayurveda Revisited.
12. Jaswal S, Jena MK, Anand V, Jaswal A, Kancharla S, Kolli P, Mandadapu G, Kumar S, Mohanty AK. Critical review on physiological and molecular features dur-ing bovine mammary gland development: recent ad-vances. Cells. 2022 Oct 21;11(20):3325.
13. What is Ayurveda? 2008. [Last accessed on 2013 Jun 22]. Available from:
14. Baghel MS. Need of new research methodology for Ayurveda. Ayu. 2011; 32:3–4. [PubMed]
15. Sharma PV, editor. Charaka Samhita of Agnivesha, Sutra Sthana, Ch. 11, Ver. 2. Varanasi: Choukhamba Orientalia; 1995. p. 114.
16. Patwardhan B. The quest for evidence-based Ay-urveda: Lessons learned. Curr Sci. 2012; 102:1406–17.
17. Morandi A, Tosto C, Sartori G, Roberti di Sarsina P. Advent of a link between Ayurveda and modern health science: The proceedings of the first interna-tional congress on ayurveda, “Ayurveda: The Meaning of Life-Awareness, Environment, and Health” March 21-22, 2009, Milan, Italy. Evid Based Complement Alternat Med 2011. 2011:929083. [PubMed]
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19. Bhowmick TK, Suresh AK, Kane SG, Joshi AC, Bellare JR. Physicochemical characterization of an Indian tra-ditional medicine, Jasada Bhasma: Detection of nanoparticles containing non-stoichiometric zinc ox-ide. J Nanopart Res. 2009; 11:655–64.
20. Jena MK, Khan FB, Ali SA, Abdullah A, Sharma AK, Yadav V, Kancharla S, Kolli P, Mandadapu G, Sahoo AK, Rath PK. Molecular complexity of mammary glands development: a review of lactogenic differen-tiation in epithelial cells. Artificial cells, nanomedi-cine, and biotechnology. 2023 Dec 31;51(1):491-508.
21. Morandi A, Sartori G, Tosto C. Ayurveda-LaMedicinatradizionale Indiana. In: Giarrelli G, di Sarsina PR, Bilvestrini B, editors. Le Medicine Non Convenzionali in Italia – Storia, Problemi e Prospet-tive di Integrazione. Milan (Italy): Franco Angeli; 2007. pp. 291–309.
22. Mishra SP, Semwal DK, Chauhan A. Scenario of Ay-urveda education in India: Some recommendations for development. University News – Association of Indian Universities. 2015; 53:3–8.
23. Naushad SM, Mandadapu G, Ramaiah MJ, Almajhdi FN, Hussain T. Mechanistic insights into TLR7-mediated clinical outcome in COVID-19 and the potential modulatory role of N-acetylcysteine.
24. Cardellina JH., 2nd Challenges and opportunities confronting the botanical dietary supplement in-dustry. J Nat Prod. 2002; 65:1073–84. [PubMed].
25. Yogini S. Jaiswal and Leonard L. Williams. J Tradit Complement Med. 2017 Jan; 7(1): 50-53. Doi: 10.1016/j.jtcme.2016.02.002 PMCID: PMC5198827| PMID: 28053888.
26. S Shilpa and C. G. Venkatesha Murthy. Ayu. 2011 Jan-Mar; 32(1): doi: 10.4103/0974-8520.85716 PMCID: PMC3215408.85716| PMID: 22131752.
27. Singh S, Kancharla S, Kolli P, Mandadapu G, Jena MK. In Silico Exploration of Phytochemicals as Potential Drug Candidates against Dipeptidyl Peptidase-4 Tar-get for the Treatment of Type 2 Diabetes. Biomedical and Biotechnology Research Journal (BBRJ). 2023 Oct 1;7(4):598-607.
28. Chamundeeswari D., Kanimozhi P., Vasanthkumar R., Sri Ramachandra J. Med. 2007, Vol. 2 pg. 39
29. Panda P., Das B., Sahu D.S., Meher S. K., Bhuyna G. C., Das B. K., Rao M. M. Talia Kalpana (Medicated oil) in Ayurveda, Res. J. Pharmacol. Pharmacodyn. 2016, Vol.81 (pg.39-41).
30. Justicia adhatoda. L Plants of the World Online. Royal Botanic Gardens, Kew. Retrieved 2019-01-26
31. Naushad SM, Mandadapu G, Ramaiah MJ, Almajhdi FN, Hussain T. The role of TLR7 agonists in modulating COVID-19 severity in subjects with loss-of-function TLR7 variants. Scientific Reports. 2023 Aug 11;13(1):13078.
32. M.G. Rasul. (2011 December). Extraction, Isolation and Characterization of Natural Products from Me-dicinal Plants. International Journal of Basic Sciences and Applied Computing. 2(6), pp. 1-6.
33. M.D. Luque de Castro, C. Priego. (2010, April). Soxhlet extraction: past and panacea. J Chroma-togram A.1217 (16), 2383–2389.
34. Ingle KP, Deshmukh AG, Padole DA, Dudhare MS, Moharil MP, Khelurkar VC. Phytochemicals: Extraction methods, identification, and detection of bioactive compounds from plant extracts. J PharmacognPhytochem. 2017; 6:32–6.
35. Vikas, S. 2012. A Review on Latest Development in the Standardization of Ayurveda Drugs. International journal of pharmaceutical research and bio-science, volume3, pp. 96-119.
Published
21/06/2024
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M, S., N. K. J, M. Y. Ch, K. Ch, C. K, M. M, and A. T. “Leaf Extract, Phytochemical Studies and Preparation of Herbal Formulation Justicia Adhatoda Lehya”. International Journal of Pharmacognosy and Chemistry, Vol. 5, no. 2, June 2024, pp. 14-22, doi:10.46796/ijpc.v5i2.590.
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