Aerva lanata: A Comprehensive Profile in the Pharmaceutical and food Industries
Abstract
Aerva lanata (L.) Juss Ex. Schult is also known as Mount knotgrass and called Polphala or Gorakha Ganga belonging to the family of Amaranthaceae. There are medicinal properties present in each part of the plant including stem, leaves, flowers, etc. This article wishes to achieve ways in order to augment the application of this plant in varied sectors and stretch the therapeutic potential of Aerva lanata species pharmaceutically, in the cosmeceutical industry, agriculturally, and the food industry. Aerva lanata and all its manufactured-products are widely used as a substantial herbal medicine system. Although they are used traditionally by a huge number of people in local areas, its potential capability of therapeutic existence is still undiscovered. This organized review is an extensive compilation of all the detailed data on phytochemistry, wide ethnopharmacological uses, medicinal characteristics and commercially applicable formula of Aerva lanata in different sectors, with the potential of antimicrobial, antiparasitic, diuretic, and anti-urolithiasis, acute renal failure, anti-asthmatic, anti-infertility, anti-hyperglycemic and anti-diabetic, hypolipidemic, hepatoprotective, immunomodulatory, anti-tumor, anti-diarrheal, anti-urolithiatic, nephroprotective, anti-ulcer, anti-HIV, anti-microbial, antioxidant etc. It will also pave a path for forthcoming research for the development of herbaceous drugs and other products to be used in agricultural and the food industry, largely contributing to the development of both these tracts.
Keywords:
Aerva lanata, pharmaceutical property of gorakhuti, Mount Knotgrass, Phytochemical constituents, pharmacological Uses, medicinal properties of gorakhuti
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References
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4. Nagaratna A, Hegde PL, Harini A. A Pharmacological review on Gorakha ganja (Aerva lanata (Linn) Juss. Ex. Schult). Journal of pharmacognosy and phytochemistry. 2015 Jan 1; 3(5).
5. PARAMASIVAM RAGAVENDRAN DS, RAJ CA, STARLIN T, GOPALAKRISHNAN VK. Phytochemical screening, antioxidant activity of Aerva lanata (L)–An Invitro study. Asian Journal of Pharmaceutical and Clinical Research. 2012; 5(2):77-81.
6. Kumar VK, Kumar PS. Ethnomedicinal plants from Vattamalai hills of Namakkal district, Tamil Nadu, India. Int J Pharm Sci Rev Res. 2011; 11:100-6.
7. Sukumaran S, Brintha TS, Subitha P, Sheebha YA, Jeeva S. Usage of medicinal plants by two cultural communities of Kanyakumari district, Tamil Nadu, South India. J Chem Pharm Res. 2014; 6:67-79.
8. Sharma N, Tanwer BS, Vijayvergia R. Study of medicinal plants in Aravali regions of Rajasthan for treatment of kidney stone and urinary tract troubles. International Journal of PharmTech Research. 2011; 3(1):110-3.
9. Sharma J, Gairola S, Gaur RD, Painuli RM. The treatment of jaundice with medicinal plants in indigenous communities of the Sub-Himalayan region of Uttarakhand, India. Journal of ethnopharmacology. 2012 Aug 30; 143(1):262-91.
10. Ayyanar M, Ignacimuthu S. Ethnobotanical survey of medicinal plants commonly used by Kani tribals in Tirunelveli hills of Western Ghats, India. Journal of ethnopharmacology. 2011 Apr 12; 134(3):851-64.
11. Bhatia H, Sharma YP, Manhas RK, Kumar K. Ethnomedicinal plants used by the villagers of district Udhampur, J&K, India. Journal of ethnopharmacology. 2014 Feb 3; 151(2):1005-18.
12. Chander MP, Kartick C, Gangadhar J, Vijayachari P. Ethno medicine and healthcare practices among Nicobarese of Car Nicobar–An indigenous tribe of Andaman and Nicobar Islands. Journal of ethnopharmacology. 2014 Dec 2; 158:18-24.
13. Rao NB, Sekhar DR, Raju DC, Nagaraju N. Folk medicine of Rayalaseema region, Andhra Pradesh: I dental protectors. Ancient science of life. 1995 Jul; 15(1):15.
14. Plant Details - Information about Aerva lanata Plant (efloraofgandhinagar.in)
15. Athira P, Nair SN. Pharmacognostic review of medicinal plant Aerva lanata. Journal of pharmaceutical sciences and Research. 2017 Sep 1;9(9):1420.
16. Aerva lanata - Wikipedia
17. Aerva lanata (Mountain knotgrass) - Herb Garden, Medicinal Plant (plantingman.com)
18. Arthi I, Ravichandiran V, Sampath Kumar KP, Subburaju T. Antiurolithiatic effect of Aerva lanata Linn extract on ethylene glycol induced urinary calculi model in rats. Int J Pharm Sci Rev Res. 2012; 17:46-50.
19. Nirmaladevi R, Chandirika JU, Annadurai G, Kalpana S, Shrinidhi Rai T. Evaluation of Aerva lanata flower extract for its antilithiatic potential in vitro and in vivo. International Journal of Pharmacy and Pharmaceutical Science Research. 2013;3(2):67-71.
20. Thangarathinam N, Jayshree N, Metha AV, Ramanathan L. Effect of polyherbal formulation on ethylene glycol induced urolithiasis. Int J Pharm Pharm Sci. 2013; 5(3):994-7.
21. Soundararajan P, Mahesh R, Ramesh T, Begum VH. Hypolipidemic activity of Aerva lanata on ethylene glycol induced calcium oxalate urolithiasis in rats. Pharmacology online. 2007; 1:557-63.
22. Soumya PS, Poornima K, Ravikumar G, Kalaiselvi M, Gomathi D, Uma C. Nephroprotective effect of Aerva lanata against mercuric chloride induced renal injury in rats. Journal of Pharmacy Research 2011; 4:2474-2476.
23. Shirwaikar A, Issac D, Malini S. Effect of Aerva lanata on cisplatin and gentamicin models of acute renal failure. Journal of ethnopharmacology. 2004 Jan 1; 90(1):81-6.
24. Faisal M, Najar FA, Ansari TA, Shakeel N. A REVIEW ARTICLE OF BISHERI BOOTI (AERVA LANATA)-ITS TRADITIONAL USES AND PHARMACOLOGICAL ACTIONS.
25. Deshmukh TA, Yadav BV, Badole SL, Bodhankar SL, Dhaneshwar SR. Antihyperglycaemic activity of alcoholic extract of Aerva lanata (L.) AL Juss. Ex JA Schultes leaves in alloxan induced diabetic mice. Journal of Applied Biomedicine. 2008 Jul 31; 6(2):81-7.
26. Appia Krishnan G, Rai VK, Nandy BC, Meena KC, Dey S, Tyagi PK, Tyagi LK. Hypoglycemic and antihyperlipidaemic effect of ethanolic extract of aerial parts of Aerva lanata Linn. in normal and alloxan induced diabetic rats. Int J Pharm Sci Drug Res. 2009; 1:191-194.
27. Riya MP, Antu KA, Pal S, Srivastava AK, Sharma S, Raghu KG. Nutraceutical potential of Aerva lanata (L.) Juss. Ex Schult ameliorates secondary complications in streptozotocininduced diabetic rats. Food Funct 2014; 5:2086-2095.
28. Sridhar N, KIRAN BV, Rudrapal M. Diuretic potential of Aerva lanata and Ecbolium ligustrinum root extracts. Asian Journal of Pharmaceutical Research and Health Care. 2014; 6(2).
29. Vetrichelvan T, Jegadeesan M, Palaniappan SM, Murali NP, Sasikumar K. Diuretic and Antiinflammatory Activities of Aerval Lanata in Rats. Indian Journal of Pharmaceutical Sciences. 2000; 62(4):300.
30. Sharma A, Sharma SC, Vaghela JS. Phytopharmacological investigation of Aerva lanata flowers with special emphasis on diuretic activity. Pharmacognosy Journal. 2010 Dec 1; 2(17):59-62.
31. Kumar D, Prasad DN, Parkash J, Bhatnagar SP, Kumar D. Antiasthmatic activity of ethanolic extract of Aerva lanata Linn. Pharmacologyonline. 2009; 2:1075-81.
32. Srujana M, Hariprasad P, Hindu MJ, Sravani P, Raju V. In vitro antibacterial activity of stem extracts of Aerva lanata Linn. Int. J. Pharm. Sci. Rev. Res. 2012; 14(1):21-3.
33. Dinnimath BM, Jalalpure SS. Studies on antimicrobial potentials of Aerva lanata fractions. International Journal of Pharmaceutical Research. 2013 Jul; 5(3):43.
34. Rajakaruna N, Harris CS, Towers GH. Antimicrobial activity of plants collected from serpentine outcrops in Sri Lanka. Pharmaceutical Biology. 2002 Jan 1; 40(3):235-44.
35. Suresh M, Rath PK, Panneerselvam A, Dhanasekaran D, Thajuddin N. Antifungal activity of selected Indian medicinal plant salts. J Global Pharma Technol. 2010; 2(4):71-4.
36. Farjeen MS, Divya SK, Jeyadoss T, Kumar MA. Quorum quenching and antibacterial activity of silver nanoparticles synthesized from medicinal plants against methicillin-resistant Staphylococcus aureus (MRSA). Int. J. Pharm. Sci... 2014; 6:358-62.
37. Anowi CF, Utoh-Nedosa AU, Onyegbule AF, Eze CC. Preliminary Phytochemical Studies and Evaluation of Antimicrobial Property of the Methanol Extract of the Roobark of Ritchiea longipedicellata Gilg Family Capparidacaea. Journal of Pharmacognosy and Phytochemistry. 2013 Mar 1; 1(6).
38. Kalirajan A, Narayanan KR, Ranjitsingh AJ, Ramalakshmi C, Parvathiraj P. Bioprospecting medicinal plant Aerva lanata Juss. Ex Schult. Flowers for potential antimicrobial activity against clinical and fish-borne pathogens.
39. Chowdhury D, Sayeed A, Islam A, Shah Alam Bhuiyan M, Astaq Mohal Khan GRM. Antimicrobial activity and cytotoxicity of Aerva lanata. Fitoterapia 2002; 73:92-94.
40. Muthukumaran P, Shanmuganathan P, Malathi C. Antioxidative and antimicrobial study of Aerva lanata. Asian Journal of Biochemical and Pharmaceutical Research. 2011 Apr;1(2):265-71.
41. Uddin SJ, Shilpi JA, Hossain MG, Sadhu SK, Jahan IA, Islam MK, Ablat A, Hossain H, Awang K, Saha S, Mondal H. Central-stimulating and analgesic activity of the ethanolic extract of Alternanthera sessilis in mice.
42. Ragavendran P, Sophia D, Arulraj C, Starlin T, Gopalakrishnan VK. Evaluation of Enzymatic and Non-Enzymatic antioxidant properties of Aerva lanata (L)-An in vitro study. Int J Pharm Pharm Sci. 2012; 4:522-6.
43. Jose JK, Kuttan G, Kuttan R. Antitumour activity of Emblica officinalis. Journal of Ethnopharmacology. 2001 May 1; 75(2-3):65-9.
44. Bhanot A, Sharma R, Singh S, Noolvi MN. In vitro anti-cancer activity of ethanol extract fractions of Aerva lanata L. Pakistan journal of biological sciences: PJBS. 2013 Nov 1; 16(22):1612-7.
45. Bharitkar YP, Hazra A, Apoorva Poduri NS, Ash A, Maulik PR, Mondal NB. Isolation, structural elucidation and cytotoxicity evaluation of a new pentahydroxy-pimarane diterpenoid along with other chemical constituents from Aerva lanata. Natural product research. 2015 Feb 1; 29(3):253-61.
46. Nevin KG, Vijayammal PL. Effect of Aerva lanata on solid tumor induced by DLA cells in mice. Fitoterapia. 2003 Sep 1; 74(6):578-82.
47. Siveen KS, Kuttan G. Modulation of humoral immune responses and inhibition of proinflammatory cytokines and nitric oxide production by 10-methoxycanthin-6-one. Immunopharmacology and immunotoxicology. 2012 Feb 1; 34(1):116-25.
48. Sharma A, Tanwar M, Nagar N, Sharma AK. Analgesic and anti-inflammatory activity of flowers extract of Aerva lanata. Advances in Pharmacology and Toxicology. 2011 Dec 1; 12(3):13.
49. Indukuri R, Prakash B, Priyadarshini RL, Vattipalli M, Rajukumar PB. Evaluation of anti-ulcer activity of Aerva lanata stem extract in rats. Indo Am. J Pharmaceut Res. 2013; 3(12):1702-8.
50. Gujjeti RP, Mamidala E. Anti-HIV activity and cytotoxic effects of Aerva lanata root extracts. Am J Phyt Clin Ther. 2014; 2:894-900.
51. Omoyeni OA, Adeyeye EI. Chemical composition, calcium, zinc and phytate interrelationships in Aerva lanata (Linn) Juss. Ex Schult leaves. Oriental Journal of Chemistry. 2009; 25(3):485.
52. Kumar G, Karthik L, Bhaskara Rao KV. Phytochemical composition and in vitro antioxidant activity of aqueous extract of Aerva lanata (L.) Juss. Ex Schult. Stem (Amaranthaceae). Asian Pac J Trop Med. 2013; 6:180-187.
53. Mukim M, Kabra A, Hano C, Drouet S, Tungmunnithum D, Chaturvedi M, Patel R. Rivea Hypocrateriformis (Desr.) Choisy: A Review of its Ethnomedicinal Uses, Phytochemistry and Biological Activities.
54. Lansky ES, Lansky S, Paavilainen HM. Harmal: The Genus Peganum. CRC Press; 2017 Oct 6.
55. Sherin DR, Sharanya N, Manojkumar TK. Potential drug leads for SARS-CoV2 from phytochemicals of Aerva lanata: a Machine Learning approach. VirusDisease. 2021 Dec; 32(4):757-65.
56. Shaheen S, Raveena RM, Jha AK. Antirheumatic Properties of Medicinal Plants: A Review. Journal of Ayurvedic and Herbal Medicine. 2021; 7(2):155-60.
57. Tewari D, Mocan A, Parvanov ED, Sah AN, Nabavi SM, Huminiecki L, Ma ZF, Lee YY, Horbańczuk JO, Atanasov AG. Ethnopharmacological approaches for therapy of jaundice: Part II. Highly used plant species from Acanthaceae, Euphorbiaceae, Asteraceae, Combretaceae, and Fabaceae families. Frontiers in pharmacology. 2017 Aug 10; 8:519.
58. https://www.shutterstock.com/image-photo/herbs-plants-aerva-lanata-l-juss-601888517
2. Varghese KJ, Anila J, Nagalekshmi R, Resiya S, Sonu J. Dasapushpam: The traditional uses and the therapeutic potential of ten sacred plants of Kerala state in India. International journal of pharmaceutical sciences and research. 2010 Oct 1; 1(10):50.
3. Rajesh R, Chitra K, Paarakh PM. Aerva lanata (Linn.) Juss. Ex Schult. –An overview.
4. Nagaratna A, Hegde PL, Harini A. A Pharmacological review on Gorakha ganja (Aerva lanata (Linn) Juss. Ex. Schult). Journal of pharmacognosy and phytochemistry. 2015 Jan 1; 3(5).
5. PARAMASIVAM RAGAVENDRAN DS, RAJ CA, STARLIN T, GOPALAKRISHNAN VK. Phytochemical screening, antioxidant activity of Aerva lanata (L)–An Invitro study. Asian Journal of Pharmaceutical and Clinical Research. 2012; 5(2):77-81.
6. Kumar VK, Kumar PS. Ethnomedicinal plants from Vattamalai hills of Namakkal district, Tamil Nadu, India. Int J Pharm Sci Rev Res. 2011; 11:100-6.
7. Sukumaran S, Brintha TS, Subitha P, Sheebha YA, Jeeva S. Usage of medicinal plants by two cultural communities of Kanyakumari district, Tamil Nadu, South India. J Chem Pharm Res. 2014; 6:67-79.
8. Sharma N, Tanwer BS, Vijayvergia R. Study of medicinal plants in Aravali regions of Rajasthan for treatment of kidney stone and urinary tract troubles. International Journal of PharmTech Research. 2011; 3(1):110-3.
9. Sharma J, Gairola S, Gaur RD, Painuli RM. The treatment of jaundice with medicinal plants in indigenous communities of the Sub-Himalayan region of Uttarakhand, India. Journal of ethnopharmacology. 2012 Aug 30; 143(1):262-91.
10. Ayyanar M, Ignacimuthu S. Ethnobotanical survey of medicinal plants commonly used by Kani tribals in Tirunelveli hills of Western Ghats, India. Journal of ethnopharmacology. 2011 Apr 12; 134(3):851-64.
11. Bhatia H, Sharma YP, Manhas RK, Kumar K. Ethnomedicinal plants used by the villagers of district Udhampur, J&K, India. Journal of ethnopharmacology. 2014 Feb 3; 151(2):1005-18.
12. Chander MP, Kartick C, Gangadhar J, Vijayachari P. Ethno medicine and healthcare practices among Nicobarese of Car Nicobar–An indigenous tribe of Andaman and Nicobar Islands. Journal of ethnopharmacology. 2014 Dec 2; 158:18-24.
13. Rao NB, Sekhar DR, Raju DC, Nagaraju N. Folk medicine of Rayalaseema region, Andhra Pradesh: I dental protectors. Ancient science of life. 1995 Jul; 15(1):15.
14. Plant Details - Information about Aerva lanata Plant (efloraofgandhinagar.in)
15. Athira P, Nair SN. Pharmacognostic review of medicinal plant Aerva lanata. Journal of pharmaceutical sciences and Research. 2017 Sep 1;9(9):1420.
16. Aerva lanata - Wikipedia
17. Aerva lanata (Mountain knotgrass) - Herb Garden, Medicinal Plant (plantingman.com)
18. Arthi I, Ravichandiran V, Sampath Kumar KP, Subburaju T. Antiurolithiatic effect of Aerva lanata Linn extract on ethylene glycol induced urinary calculi model in rats. Int J Pharm Sci Rev Res. 2012; 17:46-50.
19. Nirmaladevi R, Chandirika JU, Annadurai G, Kalpana S, Shrinidhi Rai T. Evaluation of Aerva lanata flower extract for its antilithiatic potential in vitro and in vivo. International Journal of Pharmacy and Pharmaceutical Science Research. 2013;3(2):67-71.
20. Thangarathinam N, Jayshree N, Metha AV, Ramanathan L. Effect of polyherbal formulation on ethylene glycol induced urolithiasis. Int J Pharm Pharm Sci. 2013; 5(3):994-7.
21. Soundararajan P, Mahesh R, Ramesh T, Begum VH. Hypolipidemic activity of Aerva lanata on ethylene glycol induced calcium oxalate urolithiasis in rats. Pharmacology online. 2007; 1:557-63.
22. Soumya PS, Poornima K, Ravikumar G, Kalaiselvi M, Gomathi D, Uma C. Nephroprotective effect of Aerva lanata against mercuric chloride induced renal injury in rats. Journal of Pharmacy Research 2011; 4:2474-2476.
23. Shirwaikar A, Issac D, Malini S. Effect of Aerva lanata on cisplatin and gentamicin models of acute renal failure. Journal of ethnopharmacology. 2004 Jan 1; 90(1):81-6.
24. Faisal M, Najar FA, Ansari TA, Shakeel N. A REVIEW ARTICLE OF BISHERI BOOTI (AERVA LANATA)-ITS TRADITIONAL USES AND PHARMACOLOGICAL ACTIONS.
25. Deshmukh TA, Yadav BV, Badole SL, Bodhankar SL, Dhaneshwar SR. Antihyperglycaemic activity of alcoholic extract of Aerva lanata (L.) AL Juss. Ex JA Schultes leaves in alloxan induced diabetic mice. Journal of Applied Biomedicine. 2008 Jul 31; 6(2):81-7.
26. Appia Krishnan G, Rai VK, Nandy BC, Meena KC, Dey S, Tyagi PK, Tyagi LK. Hypoglycemic and antihyperlipidaemic effect of ethanolic extract of aerial parts of Aerva lanata Linn. in normal and alloxan induced diabetic rats. Int J Pharm Sci Drug Res. 2009; 1:191-194.
27. Riya MP, Antu KA, Pal S, Srivastava AK, Sharma S, Raghu KG. Nutraceutical potential of Aerva lanata (L.) Juss. Ex Schult ameliorates secondary complications in streptozotocininduced diabetic rats. Food Funct 2014; 5:2086-2095.
28. Sridhar N, KIRAN BV, Rudrapal M. Diuretic potential of Aerva lanata and Ecbolium ligustrinum root extracts. Asian Journal of Pharmaceutical Research and Health Care. 2014; 6(2).
29. Vetrichelvan T, Jegadeesan M, Palaniappan SM, Murali NP, Sasikumar K. Diuretic and Antiinflammatory Activities of Aerval Lanata in Rats. Indian Journal of Pharmaceutical Sciences. 2000; 62(4):300.
30. Sharma A, Sharma SC, Vaghela JS. Phytopharmacological investigation of Aerva lanata flowers with special emphasis on diuretic activity. Pharmacognosy Journal. 2010 Dec 1; 2(17):59-62.
31. Kumar D, Prasad DN, Parkash J, Bhatnagar SP, Kumar D. Antiasthmatic activity of ethanolic extract of Aerva lanata Linn. Pharmacologyonline. 2009; 2:1075-81.
32. Srujana M, Hariprasad P, Hindu MJ, Sravani P, Raju V. In vitro antibacterial activity of stem extracts of Aerva lanata Linn. Int. J. Pharm. Sci. Rev. Res. 2012; 14(1):21-3.
33. Dinnimath BM, Jalalpure SS. Studies on antimicrobial potentials of Aerva lanata fractions. International Journal of Pharmaceutical Research. 2013 Jul; 5(3):43.
34. Rajakaruna N, Harris CS, Towers GH. Antimicrobial activity of plants collected from serpentine outcrops in Sri Lanka. Pharmaceutical Biology. 2002 Jan 1; 40(3):235-44.
35. Suresh M, Rath PK, Panneerselvam A, Dhanasekaran D, Thajuddin N. Antifungal activity of selected Indian medicinal plant salts. J Global Pharma Technol. 2010; 2(4):71-4.
36. Farjeen MS, Divya SK, Jeyadoss T, Kumar MA. Quorum quenching and antibacterial activity of silver nanoparticles synthesized from medicinal plants against methicillin-resistant Staphylococcus aureus (MRSA). Int. J. Pharm. Sci... 2014; 6:358-62.
37. Anowi CF, Utoh-Nedosa AU, Onyegbule AF, Eze CC. Preliminary Phytochemical Studies and Evaluation of Antimicrobial Property of the Methanol Extract of the Roobark of Ritchiea longipedicellata Gilg Family Capparidacaea. Journal of Pharmacognosy and Phytochemistry. 2013 Mar 1; 1(6).
38. Kalirajan A, Narayanan KR, Ranjitsingh AJ, Ramalakshmi C, Parvathiraj P. Bioprospecting medicinal plant Aerva lanata Juss. Ex Schult. Flowers for potential antimicrobial activity against clinical and fish-borne pathogens.
39. Chowdhury D, Sayeed A, Islam A, Shah Alam Bhuiyan M, Astaq Mohal Khan GRM. Antimicrobial activity and cytotoxicity of Aerva lanata. Fitoterapia 2002; 73:92-94.
40. Muthukumaran P, Shanmuganathan P, Malathi C. Antioxidative and antimicrobial study of Aerva lanata. Asian Journal of Biochemical and Pharmaceutical Research. 2011 Apr;1(2):265-71.
41. Uddin SJ, Shilpi JA, Hossain MG, Sadhu SK, Jahan IA, Islam MK, Ablat A, Hossain H, Awang K, Saha S, Mondal H. Central-stimulating and analgesic activity of the ethanolic extract of Alternanthera sessilis in mice.
42. Ragavendran P, Sophia D, Arulraj C, Starlin T, Gopalakrishnan VK. Evaluation of Enzymatic and Non-Enzymatic antioxidant properties of Aerva lanata (L)-An in vitro study. Int J Pharm Pharm Sci. 2012; 4:522-6.
43. Jose JK, Kuttan G, Kuttan R. Antitumour activity of Emblica officinalis. Journal of Ethnopharmacology. 2001 May 1; 75(2-3):65-9.
44. Bhanot A, Sharma R, Singh S, Noolvi MN. In vitro anti-cancer activity of ethanol extract fractions of Aerva lanata L. Pakistan journal of biological sciences: PJBS. 2013 Nov 1; 16(22):1612-7.
45. Bharitkar YP, Hazra A, Apoorva Poduri NS, Ash A, Maulik PR, Mondal NB. Isolation, structural elucidation and cytotoxicity evaluation of a new pentahydroxy-pimarane diterpenoid along with other chemical constituents from Aerva lanata. Natural product research. 2015 Feb 1; 29(3):253-61.
46. Nevin KG, Vijayammal PL. Effect of Aerva lanata on solid tumor induced by DLA cells in mice. Fitoterapia. 2003 Sep 1; 74(6):578-82.
47. Siveen KS, Kuttan G. Modulation of humoral immune responses and inhibition of proinflammatory cytokines and nitric oxide production by 10-methoxycanthin-6-one. Immunopharmacology and immunotoxicology. 2012 Feb 1; 34(1):116-25.
48. Sharma A, Tanwar M, Nagar N, Sharma AK. Analgesic and anti-inflammatory activity of flowers extract of Aerva lanata. Advances in Pharmacology and Toxicology. 2011 Dec 1; 12(3):13.
49. Indukuri R, Prakash B, Priyadarshini RL, Vattipalli M, Rajukumar PB. Evaluation of anti-ulcer activity of Aerva lanata stem extract in rats. Indo Am. J Pharmaceut Res. 2013; 3(12):1702-8.
50. Gujjeti RP, Mamidala E. Anti-HIV activity and cytotoxic effects of Aerva lanata root extracts. Am J Phyt Clin Ther. 2014; 2:894-900.
51. Omoyeni OA, Adeyeye EI. Chemical composition, calcium, zinc and phytate interrelationships in Aerva lanata (Linn) Juss. Ex Schult leaves. Oriental Journal of Chemistry. 2009; 25(3):485.
52. Kumar G, Karthik L, Bhaskara Rao KV. Phytochemical composition and in vitro antioxidant activity of aqueous extract of Aerva lanata (L.) Juss. Ex Schult. Stem (Amaranthaceae). Asian Pac J Trop Med. 2013; 6:180-187.
53. Mukim M, Kabra A, Hano C, Drouet S, Tungmunnithum D, Chaturvedi M, Patel R. Rivea Hypocrateriformis (Desr.) Choisy: A Review of its Ethnomedicinal Uses, Phytochemistry and Biological Activities.
54. Lansky ES, Lansky S, Paavilainen HM. Harmal: The Genus Peganum. CRC Press; 2017 Oct 6.
55. Sherin DR, Sharanya N, Manojkumar TK. Potential drug leads for SARS-CoV2 from phytochemicals of Aerva lanata: a Machine Learning approach. VirusDisease. 2021 Dec; 32(4):757-65.
56. Shaheen S, Raveena RM, Jha AK. Antirheumatic Properties of Medicinal Plants: A Review. Journal of Ayurvedic and Herbal Medicine. 2021; 7(2):155-60.
57. Tewari D, Mocan A, Parvanov ED, Sah AN, Nabavi SM, Huminiecki L, Ma ZF, Lee YY, Horbańczuk JO, Atanasov AG. Ethnopharmacological approaches for therapy of jaundice: Part II. Highly used plant species from Acanthaceae, Euphorbiaceae, Asteraceae, Combretaceae, and Fabaceae families. Frontiers in pharmacology. 2017 Aug 10; 8:519.
58. https://www.shutterstock.com/image-photo/herbs-plants-aerva-lanata-l-juss-601888517
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31/05/2022
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M Prajapati, G., R. S. Kadam, and D. R. Ghuge. “Aerva Lanata: A Comprehensive Profile in the Pharmaceutical and Food Industries”. International Journal of Pharmacognosy and Chemistry, Vol. 3, no. 2, May 2022, pp. 72-82, doi:10.46796/ijpc.v3i2.321.
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