A REVIEW ON THE PREDICTIVE RISK FACTORS FOR MAJOR ADVERSE CARDIOVASCULAR EVENTS IN DIABETES PATIENTS
Abstract
Diabetes is a major public health problem world-wide and is one of the prime risk factors for major adverse cardiovascular events (MACE). Classically,3 points MACE includes non fatal stroke, non fatal myocardial infarction, and cardiovascular death. The present review aims to discuss the mechanism of cardiovascular events in diabetes and the predictors or interventions to mitigate it.Keywords including ('major adverse cardiac events' and 'diabets' or 'diabetes mellitus' or 'type1 diabetes' or 'type2 diabetes' and'predictors' or 'risk factors') were searched through Google Scholar, Pubmed and Scopus databases based on PRISMA guidelines and duplicates were removed.Hyperglycaemia, abnormal lipid profile and oxidative stress are the major factors contributing to cardiac events in diabetes. Various risk factors or predictors for MACE among diabetes patients have been in research to help for the prevention or progression of these cardiac complications, reduce morbidity, mortality and economic burden of the patients.
Keywords:
Diabetes, Major adverse cardiovascular events, Predictors, Risk factors
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References
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16. Lin F-J, Tseng W-K, Yin W-H, Yeh H-I, Chen J-W, Wu C-C. Residual Risk Factors to Predict Major Adverse Cardiovascular Events in Atherosclerotic Cardiovascular Disease Patients with and without Diabetes Mellitus. Sci Rep. 2017;7(1):9179. doi:10.1038/s41598-017-08741-0.
17. Monseu M, Gand E, Saulnier P-J, et al. Acute Kidney Injury Predicts Major Adverse Outcomes in Diabetes: Synergic Impact With Low Glomerular Filtration Rate and Albuminuria. Diabetes Care. 2015;38(12):2333-2340. doi:10.2337/dc15-1222.
18. Nyström T, Holzmann MJ, Eliasson B, Kuhl J, Sartipy U. Glycemic Control in Type 1 Diabetes and Long-Term Risk of Cardiovascular Events or Death After Coronary Artery Bypass Grafting. J Am Coll Cardiol. 2015;66(5):535-543. doi:10.1016/j.jacc.2015.05.054.
19. Kasim M, Currie GM, Tjahjono M, Siswanto BB, Harimurti GM, Kiat H. Myocardial Perfusion SPECT Utility in Predicting Cardiovascular Events Among Indonesian Diabetic Patients. Open Cardiovasc Med J. 2013;7:82-89. doi:10.2174/1874192401307010082.
20. Shinohara T. Interleukin-6 as an Independent Predictor of Future Cardiovascular Events in Patients with Type-2 Diabetes without Structural Heart Disease. J Clin Exp Cardiolog. 2012;03(09). doi:10.4172/2155-9880.1000209.
21. Hung W-C, Wang C-P, Lu L-F, et al. Circulating adiponectin level is associated with major adverse cardiovascular events in type 2 diabetic patients with coronary artery disease. Endocr J. 2010;57(9):793-802. doi:10.1507/endocrj.k10e-020.
22. Gazzaruso C, Solerte SB, Pujia A, et al. Erectile Dysfunction as a Predictor of Cardiovascular Events and Death in Diabetic Patients With Angiographically Proven Asymptomatic Coronary Artery Disease. Journal of the American College of Cardiology. 2008;51(21):2040-2044. doi:10.1016/j.jacc.2007.10.069
2. Bullard KM, Cowie CC, Lessem SE, et al. Prevalence of Diagnosed Diabetes in Adults by Diabetes Type - United States, 2016. MMWR Morb Mortal Wkly Rep. 2018;67(12):359-361. doi:10.15585/mmwr.mm6712a2.
3. Einarson TR, Acs A, Ludwig C, Panton UH. Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007-2017. Cardiovasc Diabetol. 2018;17(1):83. doi:10.1186/s12933-018-0728-6.
4. Poudel I, Tejpal C, Rashid H, Jahan N. Major Adverse Cardiovascular Events: An Inevitable Outcome of ST-elevation myocardial infarction? A Literature Review. Cureus. 2019;11(7):e5280. doi:10.7759/cureus.5280.
5. Kumar A, Patel DR, Wolski KE, et al. Baseline fasting plasma insulin levels predict risk for major adverse cardiovascular events among patients with diabetes and high-risk vascular disease: Insights from the ACCELERATE trial. Diab Vasc Dis Res. 2019;16(2):171-177. doi:10.1177/1479164119827604.
6. Dokken BB. The Pathophysiology of Cardiovascular Disease and Diabetes: Beyond Blood Pressure and Lipids. Diabetes Spectr. 2008;21(3):160-165. doi:10.2337/diaspect.21.3.160.
7. Leon BM, Maddox TM. Diabetes and cardiovascular disease: Epidemiology, biological mechanisms, treatment recommendations and future research. World J Diabetes. 2015;6(13):1246-1258. doi:10.4239/wjd.v6.i13.1246.
8. Yiannoullou P, Summers A, Goh SC, et al. Major Adverse Cardiovascular Events Following Simultaneous Pancreas and Kidney Transplantation in the United Kingdom. Diabetes Care. 2019;42(4):665-673. doi:10.2337/dc18-2111.
9. Jensen MT, Sogaard P, Gustafsson I, et al. Echocardiography improves prediction of major adverse cardiovascular events in a population with type 1 diabetes and without known heart disease: the Thousand & 1 Study. Diabetologia. 2019;62(12):2354-2364. doi:10.1007/s00125-019-05009-2.
10. Liao K-M, Chang C-W, Wang S-H, Chang Y-T, Chen Y-C, Wang G-C. The first harmonic of radial pulse wave predicts major adverse cardiovascular and microvascular events in patients with type 2 diabetes. J Diabetes Complicat. 2019;33(11):107420. doi:10.1016/j.jdiacomp.2019.107420.
11. Gerbaud E, Darier R, Montaudon M, et al. Glycemic Variability Is a Powerful Independent Predictive Factor of Midterm Major Adverse Cardiac Events in Patients With Diabetes With Acute Coronary Syndrome. Diabetes Care. 2019;42(4):674-681. doi:10.2337/dc18-2047.
12. Xing Z, Tang L, Chen J, et al. Association of predicted lean body mass and fat mass with cardiovascular events in patients with type 2 diabetes mellitus. CMAJ. 2019;191(38):E1042-E1048. doi:10.1503/cmaj.190124.
13. Young JB, Gauthier-Loiselle M, Bailey RA, et al. Development of predictive risk models for major adverse cardiovascular events among patients with type 2 diabetes mellitus using health insurance claims data. Cardiovasc Diabetol. 2018;17(1):118. doi:10.1186/s12933-018-0759.
14. Blanc-Bisson C, Velayoudom-Cephise FL, Cougnard-Gregoire A, et al. Skin autofluorescence predicts major adverse cardiovascular events in patients with type 1 diabetes: a 7-year follow-up study. Cardiovasc Diabetol. 2018;17(1):82. doi:10.1186/s12933-018-0718-8.
15. Chisalita IS, Wijkman M, Chong LT, et al. Toe brachial index predicts major adverse cardiovascular events in patients with type 2 diabetes. EJEA. May 2018. doi:10.1530/endoabs.56.OC4.2.
16. Lin F-J, Tseng W-K, Yin W-H, Yeh H-I, Chen J-W, Wu C-C. Residual Risk Factors to Predict Major Adverse Cardiovascular Events in Atherosclerotic Cardiovascular Disease Patients with and without Diabetes Mellitus. Sci Rep. 2017;7(1):9179. doi:10.1038/s41598-017-08741-0.
17. Monseu M, Gand E, Saulnier P-J, et al. Acute Kidney Injury Predicts Major Adverse Outcomes in Diabetes: Synergic Impact With Low Glomerular Filtration Rate and Albuminuria. Diabetes Care. 2015;38(12):2333-2340. doi:10.2337/dc15-1222.
18. Nyström T, Holzmann MJ, Eliasson B, Kuhl J, Sartipy U. Glycemic Control in Type 1 Diabetes and Long-Term Risk of Cardiovascular Events or Death After Coronary Artery Bypass Grafting. J Am Coll Cardiol. 2015;66(5):535-543. doi:10.1016/j.jacc.2015.05.054.
19. Kasim M, Currie GM, Tjahjono M, Siswanto BB, Harimurti GM, Kiat H. Myocardial Perfusion SPECT Utility in Predicting Cardiovascular Events Among Indonesian Diabetic Patients. Open Cardiovasc Med J. 2013;7:82-89. doi:10.2174/1874192401307010082.
20. Shinohara T. Interleukin-6 as an Independent Predictor of Future Cardiovascular Events in Patients with Type-2 Diabetes without Structural Heart Disease. J Clin Exp Cardiolog. 2012;03(09). doi:10.4172/2155-9880.1000209.
21. Hung W-C, Wang C-P, Lu L-F, et al. Circulating adiponectin level is associated with major adverse cardiovascular events in type 2 diabetic patients with coronary artery disease. Endocr J. 2010;57(9):793-802. doi:10.1507/endocrj.k10e-020.
22. Gazzaruso C, Solerte SB, Pujia A, et al. Erectile Dysfunction as a Predictor of Cardiovascular Events and Death in Diabetic Patients With Angiographically Proven Asymptomatic Coronary Artery Disease. Journal of the American College of Cardiology. 2008;51(21):2040-2044. doi:10.1016/j.jacc.2007.10.069
Published
30/06/2020
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How to Cite
Srinivas Pasula, S. P., T. J. Talha Jabeen, G. K. Greeshma Kothakoti, B. D. P. Beda Durga Prasad, and A. S. R. A. Srinivasa Rao. “A REVIEW ON THE PREDICTIVE RISK FACTORS FOR MAJOR ADVERSE CARDIOVASCULAR EVENTS IN DIABETES PATIENTS”. International Journal of Health Care and Biological Sciences, Vol. 1, no. 1, June 2020, pp. 39-45, https://saapjournals.org/index.php/ijhcbs/article/view/24.
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Review Articles
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