https://saapjournals.org/index.php/ijhcbs <p>International Journal of Health Care and Biological Sciences (IJHCBS) is an international online open access, peer-reviewed, quarterly journal Publish Health as well as Life sciences field on the basis of its originality, and serve as a means for scientific information exchange in the international Health Care and Biological science with a strong emphasis on originality and scientific quality. IJHCBS aims to publish quarterly and accepts for publishing original and research articles, review articles, case studies, and reports short communication, meta-analysis.</p> International Journal of Health Care and Biological Sciences en-US International Journal of Health Care and Biological Sciences 2582-7499 https://saapjournals.org/index.php/ijhcbs/article/view/631 <p>Alpinia calcarata, commonly known as Dwarf Cardamom or Snap Ginger, is a perennial herb in the Zingiberaceae family. Various doses of the extract be administer including a&nbsp; dose of 2000 mg/kg and&nbsp; from which the low doses of 100 mg/kg and high dose was 200 mg/kg. At the high dose, no fatalities or adverse health effects were observed, indicating that the extract is well-tolerated. The positive safety profile at this dosage supports the selection of lower doses for further therapeutic evaluation. These findings suggest that the ethanolic extract possesses a favorable safety margin, positioning it as a promising candidate for subsequent pharmacological studies.</p> Madhu Chandaka Copyright (c) 2024 https://creativecommons.org/licenses/by-nc/4.0 2024-10-07 2024-10-07 1 5 10.46795/ijhcbs.v5i4.631 https://saapjournals.org/index.php/ijhcbs/article/view/633 <p>3D printing, or additive manufacturing, is transforming the pharmaceutical industry by enabling the precise fabrication of complex drug formulations, personalized dosages, and advanced drug delivery systems. Initially utilized in aerospace and automotive industries, 3D printing has rapidly been adopted in pharmaceuticals, offering new opportunities for customized medicine, rapid prototyping, and on-demand drug manufacturing. This review explores the current advancements in 3D printing technologies, such as Fused Deposition Modeling (FDM), Stereolithography (SLA), Selective Laser Sintering (SLS), Inkjet Printing, and Extrusion-Based Printing. These technologies have shown significant potential in creating personalized medication, developing complex drug delivery systems, and addressing pediatric and geriatric populations' unique needs. Despite these advancements, challenges still need to be addressed, including regulatory hurdles, technical limitations, scalability issues, and intellectual property concerns. Future directions include integrating 3D printing with digital health technologies for real-time patient monitoring and personalized treatment, developing advanced materials and printing technologies, and evolving regulatory frameworks to accommodate the growing use of 3D printing in pharmaceuticals. Collaborative research and development are crucial to overcoming these challenges and realizing the full potential of 3D printing in revolutionizing drug manufacturing and delivery, particularly in improving global accessibility to essential medicines.</p> Sanket J Soni Copyright (c) 2024 https://creativecommons.org/licenses/by-nc/4.0 2024-10-31 2024-10-31 6 12 10.46795/ijhcbs.v5i4.633