PATIENT-CENTRIC PHARMACEUTICAL MANUFACTURING USING 3D PRINTING TECHNOLOGIES
Abstract
Three-dimensional (3D) printing, also called as additive manufacturing, is a transformative technology that utilizes computer-aided design (CAD) software and digital programming to create three-dimensional objects through the precise layer-by-layer deposition or solidification of materials. In pharmaceutical applications, medicinal substances are planned in a three-dimensional format using CAD systems and converted into machine-readable files. These files define the external geometry of the dosage form, which is then digitally separated into printable layers and manufactured sequentially by the printer.
Keywords:
3D printing, additive manufacturing, drug printing, personalized medicine, pharmaceutical manufacturing, innovative drug formulations, pharmaceutical dosage forms, tailored drug release
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References
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3. Andreadis II, Gioumouxouzis CI, Eleftheriadis GK, Fatouros DG. The advent of a new era in digital healthcare: a role for 3D printing technologies in drug manufacturing. Pharmaceutics. 2022;14(3):609.
4. Prasad LK, Smyth H. 3D printing technologies for drug delivery: a review. Drug Dev Ind Pharm. 2016;42(7):1019-1031.
5. Konta AA, García-Piña M, Serrano DR. Personalised 3D printed medicines: which techniques and polymers are more successful? Bioengineering (Basel). 2017;4(4):79.
6. Wang J, Goyanes A, Gaisford S, Basit AW. Stereolithographic (SLA) 3D printing of oral modified-release dosage forms. Int J Pharm. 2016;503(1-2):207-212.
7. Srinivas L, Jaswitha M, Manikanta V, Bhavya B, Himavant BD. 3D printing in pharmaceutical technology: a review. Int Res J Pharm. 2019;10(2):8-17.
8. Alhnan MA, Okwuosa TC, Sadia M, Wan KW, Ahmed W, Arafat B. Emergence of 3D printed dosage forms: opportunities and challenges. Pharm Res. 2016;33(8):1817-1832.
9. Tracy T, Wu L, Liu X, Cheng S, Li X. 3D printing: innovative solutions for patients and pharmaceutical industry. Int J Pharm. 2023;631:122480.
10. Wang S, Chen X, Han X, Hong X, Li X, Zhang H, Li M, Wang Z, Zheng A. A review of 3D printing technology in pharmaceutics: technology and applications, now and future. Pharmaceutics. 2023;15(2):416.
11. Trenfield SJ, Awad A, Goyanes A, Gaisford S, Basit AW. 3D printing pharmaceuticals: drug development to frontline care. Trends Pharmacol Sci. 2018;39(5):440-451.
12. Wu G, Wu W, Zheng Q, Li J, Zhou J, Hu Z. Experimental study of PLLA/INH slow release implant fabricated by three-dimensional printing technique and drug release characteristics in vitro. Biomed Eng Online. 2014;13(1):97.
13. Rao C. Evaluation of antiulcer activity of Picrasma quassioides Bennett aqueous extract in rodents. Vedic Res Int Phytomedicine. 2013.
14. Gindi S, Methra T, Chandu BR, Boyina R, Dasari V. Antiurolithiatic and in vitro antioxidant activity of leaves of Ageratum conyzoides in rats. World J Pharm Pharm Sci. 2013;2(2):636-649.
15. Nama S, Chandu BR, Awen BZ, Khagga M. Development and validation of a new RP-HPLC method for the determination of aprepitant in solid dosage forms. Trop J Pharm Res. 2011;10(4):489-494.
16. Kiranmai M, Renuka P, Brahmaiah B, Chandu BR. Vitamin D as a promising anticancer agent. Int J Res Pharm Chem. 2012;2(1):108-112.
17. Degapati RT. Novel approaches in transdermal drug delivery system. J Multidiscip Res. 2025:20-25.
18. Adiki SK, Lahari K, Dey B, Khalf AM, Al-Sharif SM, Diaf SR, Katakam P, Chandu BR. Validated UV method development for the simultaneous estimation of rabeprazole sodium and cinitapride in tablets.
19. Sarvani V, Elisha RP, Nama S, Pola LM, Rao CB. Process validation: an essential process in pharmaceutical industry. Int J Med Chem Anal. 2013;3(2):49-52.
20. Avinash M, Suryaprabha M, Sreekanth N, Dineshreddy B, Baburao CH. Advanced and recent emerging trends in insulin drug delivery systems. Int J Bio-Pharma Res. 2012;1:1-8.
Published
05/06/2026
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How to Cite
Mekala, U. M. “PATIENT-CENTRIC PHARMACEUTICAL MANUFACTURING USING 3D PRINTING TECHNOLOGIES”. International Journal of Health Care and Biological Sciences, Vol. 7, no. 2, June 2026, pp. 24-28, https://saapjournals.org/index.php/ijhcbs/article/view/878.
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Review Articles
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