DEVELOPMENT AND EVALUATION OF MORINGA SUSPENSION BY USING XANTHANGUM AND VEEGUM AND COMPARING WITH MARKETED PRODUCT

Vinod Kumar K

doi:10.46795/ijhcbs.v7i1.821

K.Vinod Kumar 1Professor, Department of Pharmaceutics, St.Ann’s College of Pharmacy, Chirala.

DOI https://doi.org/10.46795/ijhcbs.v7i1.821

Abstract

Moringa oleifera is a highly valued medicinal plant known for its extensive nutritional and pharmacological benefits. It contains various bioactive constituents such as flavonoids, phenolic compounds, alkaloids, vitamins, and minerals that exhibit antioxidant, anti-inflammatory, antimicrobial, and antidiabetic properties. Despite its therapeutic potential, the direct use of Moringa powder may present challenges such as poor palatability, variable dosing, and reduced bioavailability of certain phytoconstituents. To overcome these limitations, the present study was undertaken to develop and evaluate an oral Moringa suspension with improved stability, uniformity, and patient compliance. The suspension was formulated using suitable suspending agents such as xanthan gum and veegum to ensure proper dispersion of the Moringa extract. Additional excipients including preservatives, sweeteners, and flavoring agents were incorporated to enhance stability and acceptability. The formulated suspension was evaluated for various physicochemical parameters including organoleptic properties, pH, viscosity, sedimentation volume, redispersibility, particle size distribution, and in vitro stability studies. The results indicated that the prepared suspension exhibited satisfactory physical stability, good sedimentation characteristics with easy redispersibility, acceptable viscosity, and uniform drug content. Stability studies confirmed that the formulation remained stable under recommended storage conditions without significant changes in physical appearance or pH. The developed Moringa suspension demonstrated desirable pharmaceutical characteristics and improved patient compliance, making it a promising herbal oral dosage form for therapeutic use. This formulation approach may enhance the effectiveness and accessibility of Moringa-based herbal preparations in clinical practice.

Keywords: Moringa oleifera, Oral Suspension, Flavonoids, Xanthan Gum, Bioavailability, Physicochemical Evaluation

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