A Brief Review of its Pharmacological Properties of Acalypha Indica
Abstract
With more individuals looking for health solutions and treatments free from artificial chemical side effects, medicinal plants are making the transition from being used only in border areas to mainstream settings. More than 3500 plants have official medical recognition in India. In India, around 6000 plants are reportedly used in folk, traditional, and herbal medicine. The traditional medicine system of India and many other nations uses this plant, which is said to have anti-inflammatory, anti-tumor, anti-diabetic, antioxidant, anti-bacterial, antifungal, hepatoprotective, and anti-cancer properties. It is also used to monitor wound and ulcer healing. Glycosides, flavonoids, and tannins are all recognized to be abundant in it. Acalypha indicica's therapeutic benefits, medicinal qualities, and studies on its secondary metabolites demonstrate its significance as a useful medication.
Keywords:
Acalypha indicia, pharmacological, anti-cancer, wound healing;, glycosides
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References
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7. Namballa M, Adimulapu A, Jesudasan RE. QbD Assisted Optimization of Microwave-assisted Synthesis of Polyacrylamide Grafted Tragacanth: Characterization and Instrumental Analysis. Current Microwave Chemistry. 2024 Apr 1;11(1):16-29.
8. Pendyala V, Baburao C, Chandrasekhar KB. Studies on some physicochemical properties of Leucaena Leucocephala bark gum. Journal of advanced pharmaceutical technology & research. 2010 Apr 1;1(2):253-9.
9. Takle VV, Savad RV, Kandalkar AM, Akarte AM, Patel AM. Pharmacognostic and Phytochemical investigations of aerial parts of Acalypha indica Linn. Pharmacognosy Journal. 2011 Apr 1;3(21):33-5.
10. Beena J, Molly M. Anti-oxidant studies and chemical investigation of ethanol extract of Acalypha indica Linn. Drug plants I. 2010:261-79.
11. Sanseera D, Niwatananun W, Liawruangrath B, Liawruangrath S, Baramee A, Trisuwan K, Pyne SG. Antioxidant and anticancer activities from aerial parts of Acalypha indica Linn.
12. Chowdary KP, Chandra DU, Mahesh N, Reddy TM, Gopaiah KV. Enhancement of dissolution rate and formulation development of pioglitazone-a BCS class II drug. J. Pharm. Res. 2011 Nov;4:3862-3.
13. Vogel HG, editor. Drug discovery and evaluation: pharmacological assays. Springer Science & Business Media; 2002 Jun 13.
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15. Chengaiah B, Kumar KM, Alagusundaram M, Sasikala C, Chetty CM. In vitro anthelmintic activity of roots of Acalypha indica Linn. International journal of pharmtech research. 2009 Oct;1(4):1499-502.
16. Garai Ranju GR, Sutar Niranjan SN, Kumar PS, Kumar PV, Kumar PS. In vitro anthelmintic activity of Acalypha indica leaves extracts.
17. Alves TM, Silva AF, Brandão M, Grandi TS, Smânia ED, Smânia Júnior A, Zani CL. Biological screening of Brazilian medicinal plants. Memórias do Instituto Oswaldo Cruz. 2000;95:367-73.
18. Batubara I, Wahyuni WT, Firdaus I. Utilization of anting-anting (Acalypha indica) leaves as antibacterial. InIOP Conference Series: Earth and Environmental Science 2016 (Vol. 31, No. 1, p. 012038). IOP Publishing.
19. Amarnath K, Dhanabal J, Agarwal I, Seshadry S. Cytotoxicity induction by ethanolic extract of Acalypha indica loaded casein-chitosan microparticles in human prostate cancer cell line in vitro. Biomedicine & Preventive Nutrition. 2014 Jul 1;4(3):445-50.
20. Chekuri S, Panjala S, Anupalli RR. Cytotoxic activity of Acalypha indica L. hexane extract on breast cancer cell lines (MCF-7). The Journal of Phytopharmacology. 2017;6(5):264-8.
21. Kumar KR, Nagaraju GV, Subrahmanyam SN, Nagarani K, Shareef S, Tennygilphin M, Namballa M. Assessment on Elements Involving the Academic Performance among Pharmacy Students: A Cross-Sectional Observational Study. Int J Cur Res Rev| Vol. 2021 Dec;13(23):141.
22. Nandhakumar M, Tamil Iniyan G, Senthilkumar M, Dinesh Kumar B, Mitra A. In vitro assay of alpha amylase inhibitory activity of Indian medicinal herb Acalypha indica. J Clin Diagn Res. 2009 Apr;3:1475-8.
23. Hungeling M, Lechtenberg M, Fronczek FR, Nahrstedt A. Cyanogenic and non-cyanogenic pyridone glucosides from Acalypha indica (Euphorbiaceae). Phytochemistry. 2009 Jan 1;70(2):270-7.
24. Selvamani S, Balamurugan S. Antibacterial and antifungal activities of different organic solvent extracts of Acalypha indica (Linn.). Asian Journal of Plant Science & Research. 2011.
25. Sakthi SS, Geetha M, Saranraj P. Pharmacological screening of Datura metel and Acalypha indica for its antifungal activity against pathogenic fungi. International journal of pharmaceutical science and health care. 2011;2(1):15-30.
http://www.arjournals.org/index.php/ijpm/indexReferences
2. Nama S, Chandu BR, Awen BZ, Khagga M. Development and validation of a new RP-HPLC method for the determination of aprepitant in solid dosage forms. Tropical Journal of Pharmaceutical Research. 2011;10(4):491-7.
3. Sivasankari B, Anandharaj M, Gunasekaran P. An ethnobotanical study of indigenous knowledge on medicinal plants used by the village peoples of Thoppampatti, Dindigul district, Tamilnadu, India. Journal of ethnopharmacology. 2014 Apr 28;153(2):408-23.
4. Kirtikar KR, Baman D. Indian medicinal plants. Indian Medicinal Plants. Saha R, Ahmed A, 2011b. Phytochemical constituents and pharmacological activities of Acalyphus Indica Linn: A review. International Journal of Pharmaceutical Sciences Research. 1918;2:1900-4.
5. Hwisa NT, Chandu BR, Katakam P, Nama S. Pharmacognostical studies on the leaves of Ficus altissima blume. Journal of Applied Pharmaceutical Science. 2013 May 12;3(4,):S56-8.
6. Scaffidi A, Algar D, Bohman B, Ghisalberti EL, Flematti G. Identification of the cat attractants isodihydronepetalactone and isoiridomyrmecin from Acalypha indica. Australian Journal of Chemistry. 2016 Jan 21;69(2):169-73.
7. Namballa M, Adimulapu A, Jesudasan RE. QbD Assisted Optimization of Microwave-assisted Synthesis of Polyacrylamide Grafted Tragacanth: Characterization and Instrumental Analysis. Current Microwave Chemistry. 2024 Apr 1;11(1):16-29.
8. Pendyala V, Baburao C, Chandrasekhar KB. Studies on some physicochemical properties of Leucaena Leucocephala bark gum. Journal of advanced pharmaceutical technology & research. 2010 Apr 1;1(2):253-9.
9. Takle VV, Savad RV, Kandalkar AM, Akarte AM, Patel AM. Pharmacognostic and Phytochemical investigations of aerial parts of Acalypha indica Linn. Pharmacognosy Journal. 2011 Apr 1;3(21):33-5.
10. Beena J, Molly M. Anti-oxidant studies and chemical investigation of ethanol extract of Acalypha indica Linn. Drug plants I. 2010:261-79.
11. Sanseera D, Niwatananun W, Liawruangrath B, Liawruangrath S, Baramee A, Trisuwan K, Pyne SG. Antioxidant and anticancer activities from aerial parts of Acalypha indica Linn.
12. Chowdary KP, Chandra DU, Mahesh N, Reddy TM, Gopaiah KV. Enhancement of dissolution rate and formulation development of pioglitazone-a BCS class II drug. J. Pharm. Res. 2011 Nov;4:3862-3.
13. Vogel HG, editor. Drug discovery and evaluation: pharmacological assays. Springer Science & Business Media; 2002 Jun 13.
14. Crunkhorn P, Meacock SC. Mediators of the inflammation induced in the rat paw by carrageenin. British journal of pharmacology. 1971 Jul;42(3):392-402.
15. Chengaiah B, Kumar KM, Alagusundaram M, Sasikala C, Chetty CM. In vitro anthelmintic activity of roots of Acalypha indica Linn. International journal of pharmtech research. 2009 Oct;1(4):1499-502.
16. Garai Ranju GR, Sutar Niranjan SN, Kumar PS, Kumar PV, Kumar PS. In vitro anthelmintic activity of Acalypha indica leaves extracts.
17. Alves TM, Silva AF, Brandão M, Grandi TS, Smânia ED, Smânia Júnior A, Zani CL. Biological screening of Brazilian medicinal plants. Memórias do Instituto Oswaldo Cruz. 2000;95:367-73.
18. Batubara I, Wahyuni WT, Firdaus I. Utilization of anting-anting (Acalypha indica) leaves as antibacterial. InIOP Conference Series: Earth and Environmental Science 2016 (Vol. 31, No. 1, p. 012038). IOP Publishing.
19. Amarnath K, Dhanabal J, Agarwal I, Seshadry S. Cytotoxicity induction by ethanolic extract of Acalypha indica loaded casein-chitosan microparticles in human prostate cancer cell line in vitro. Biomedicine & Preventive Nutrition. 2014 Jul 1;4(3):445-50.
20. Chekuri S, Panjala S, Anupalli RR. Cytotoxic activity of Acalypha indica L. hexane extract on breast cancer cell lines (MCF-7). The Journal of Phytopharmacology. 2017;6(5):264-8.
21. Kumar KR, Nagaraju GV, Subrahmanyam SN, Nagarani K, Shareef S, Tennygilphin M, Namballa M. Assessment on Elements Involving the Academic Performance among Pharmacy Students: A Cross-Sectional Observational Study. Int J Cur Res Rev| Vol. 2021 Dec;13(23):141.
22. Nandhakumar M, Tamil Iniyan G, Senthilkumar M, Dinesh Kumar B, Mitra A. In vitro assay of alpha amylase inhibitory activity of Indian medicinal herb Acalypha indica. J Clin Diagn Res. 2009 Apr;3:1475-8.
23. Hungeling M, Lechtenberg M, Fronczek FR, Nahrstedt A. Cyanogenic and non-cyanogenic pyridone glucosides from Acalypha indica (Euphorbiaceae). Phytochemistry. 2009 Jan 1;70(2):270-7.
24. Selvamani S, Balamurugan S. Antibacterial and antifungal activities of different organic solvent extracts of Acalypha indica (Linn.). Asian Journal of Plant Science & Research. 2011.
25. Sakthi SS, Geetha M, Saranraj P. Pharmacological screening of Datura metel and Acalypha indica for its antifungal activity against pathogenic fungi. International journal of pharmaceutical science and health care. 2011;2(1):15-30.
Published
18/08/2024
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Shaik, R. “A Brief Review of Its Pharmacological Properties of Acalypha Indica”. International Journal of Health Care and Biological Sciences, Vol. 5, no. 3, Aug. 2024, pp. 12-15, doi:10.46795/ijhcbs.v5i3.618.
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