An updated review on liposomes- a modified dosage form
Abstract
The first Nano medication to be approved for clinical usage was liposomes. Liposomes are being utilized more frequently for targeted drug delivery because of their incredible capacity to prevent drug deterioration and minimize unwanted side effects. In Liposomes, the drug can either be integrated inside the aqueous space (hydrophilic drugs) or inside the phospholipid's bilayer (hydrophobic drugs). The classification of liposomes, production of liposomes, applications, their advantages and drawbacks are the main topics covered in this review. Today, most researchers are becoming more and more interested in liposomes. As they are effective against a certain condition, and are simple to make, and have several additional benefits than others. This review covered liposomes as a modified dosage form, covering their present status, drawbacks, and applications. Numerous liposome-based formulations with higher drug concentrations have been developed as liposomes are effective as therapeutic agents.
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References
2. Nwobodo NN, Adamude FA, Dingwoke EJ, Ubhenin A. Formulation and evaluation of elastic liposomes of decitabine prepared by rotary evaporation method. Universal Journal of Pharmaceutical Research 2019; 4(3):1-5.
3. Dua JS, Rana AC, Bhandari AK. Liposome: methods of preparation and applications. Int J Pharm Stud Res. 2012 Apr;3(2):14-20.
4. John DF, Yunus AA, Chigbo UJ, Paul US, Ikenna E. Tolnaftate loaded liposomes-design, and in-vitro evaluation. Universal Journal of Pharmaceutical Research 2016; 1(2): 29-31.
5. Filipczak N, Pan J, Yalamarty SS, Torchilin VP. Recent advancements in liposome technology. Advanced drug delivery reviews. 2020 Jan 1;156:4-22.
6. ALGIN YAPAR E, ESENTÜRK İ, ŞAHİNER A, HALAT E, KARA BA, BALA R, SINDHU RK. Cosmetotextiles and evaluation of their performance. Universal Journal of Pharmaceutical Research 2021; 6(3):64-67.
7. Sharma D, Ali AA, Trivedi LR. An Updated Review on: Liposomes as drug delivery system. PharmaTutor. 2018 Feb 1;6(2):50-62.
8. Elsaied EH, Dawaba HM, Ibrahim ESA, Afouna MI. Effect of pegylated edge activator on Span 60 based nanovesicles: comparison between Myrj 52 and Myrj 59. Universal Journal of Pharmaceutical Research 2019;4(4):1-8.
9. Sherpa LS, Kumar I, Chaudhary A, Lepcha B. Liposomal drug delivery system: Method of preparations and applications. Journal of Pharmaceutical Sciences and Research. 2020 Sep 1;12(9):1192-7.
10. Chauhan N, Kumar K, Pant NC. An updated review on transfersomes: a novel vesicular system for transdermal drug delivery. Universal Journal of Pharmaceutical Research 2017; 2(4): 42-45.
11. Shah S, Dhawan V, Holm R, Nagarsenker MS, Perrie Y. Liposomes: Advancements and innovation in the manufacturing process. Advanced drug delivery reviews. 2020 Jan 1;154:102-22.
12. Anwar W, Dawaba HM, Afouna MI, Samy AM.Screening study for formulation variables in preparation and characterization of candesartan cilexetil loaded nanostructured lipid carriers. Universal Journal of Pharmaceutical Research 2019; 4(6):8-19.
13. Yusaf R, Nawaz R, Hayat S, Khursheed A, Zafar N, Ahmad A, Bashir I, Alvi N, Sajid M, Majeed I. Structural components of liposomes and characterization tools. American Journal of Pharm Research. 2014;4(08).
14. Ojha A, Madhav NVS, Tyagi S, Basnet V, Parveen H. An exhaustive statistic on current mucoadhesive intravaginal drug delivery methodologies. Universal Journal of Pharmaceutical Research. 2017; 2(6): 76-84.
15. Akbarzadeh A, Rezaei-Sadabady R, Davaran S, Joo SW, Zarghami N, Hanifehpour Y, Samiei M, Kouhi M, Nejati- Koshki K. Liposome: classification, preparation, and applications. Nanoscale research letters. 2013 Dec;8:1-9.
16. Bhartee Pathak, Kapil Kumar. Buccal drug delivery system: a tool for the effective delivery of pharmaceuticals. Universal Journal of Pharmaceutical Research 2017; 2(3): 19-24.
17. Pradhan B, Kumar N, Saha S, Roy A. Liposome: Method of preparation, advantages, evaluation and its application. Journal of Applied Pharmaceutical Research. 2015 Nov 30;3(3):01-8.
18. Singh S, Virmani T, Virmani R, Kumar P, Mahlawat G. Fast dissolving drug delivery systems: formulation, preparation techniques and evaluation. Universal Journal of Pharmaceutical Research 2018; 3(4): 56-64.
19. Farooque F, Wasi M, Mughees MM. Liposomes as Drug Delivery System: An Updated Review. Journal of Drug Delivery and Therapeutics. 2021 Oct 15;11(5-S):149-58.
20. Ojha A, Madhav NVS, Tyagi S, Basnet V, Parveen H. An exhaustive statistic on current mucoadhesive
21. intravaginal drug delivery methodologies. Universal Journal of Pharmaceutical Research. 2017; 2(6): 76-84.
22. Türkmen A, Esentürk-Güzel İ, Kara BA. Innovative drug delivery systems for infectious diseases of the skin. Universal Journal of Pharmaceutical Research 2022; 7(4):68-76.
23. Paliwal S, Kaur G, Arya KKR. Formulation and characterization of topical nano emulgel of terbinafine. Universal Journal of Pharmaceutical Research 2018; 3(6): 28-34.
24. Shailesh S, Neelam S, Sandeep K, Gupta GD. Liposomes: a review. Journal of pharmacy research. 2009 Jul;2(7):1163- 7.
25. Kumar V, Kumar K, Joshi A, Teotia D. A comprehensive review on liposomes: A vesicular system for drug delivery. GSC Biological and Pharmaceutical Sciences. 2022;18(2):331-7.

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