International Journal of Alternative and Complementary Medicine

Ayurvedic Nanoformulations for the Management of Diabetes Mellitus

Sri Ram Sailesh R, Jayanth K, Tanmayee K, Rohit Roshan MVS — Wed, 15 Apr 2026 00:00:00 +0530

Diabetes mellitus remains a global health challenge, necessitating innovative therapeutic approaches that combine traditional knowledge with modem advancements. Ayurveda, with its rich repository of medicinal herbs and holistic treatment principles, offers promising solutions, particularly when integrated with nanotechnology to enhance bioavailability and efficacy. This systematic literature review examines the current state of research on Ayurvedic nanoformulations for diabetes management, focusing on their development, mechanisms, and therapeutic outcomes. We analyze the convergence of Ayurvedic nanomedicine and technology, the role of specific herbs and their bioactive compounds, and the methodologies employed in formulating and evaluating these nanoformulations. The review synthesizes evidence from peer-reviewed studies to identify trends, gaps, and future directions in this interdisciplinary field. Our findings reveal that Ayurvedic nanoformulations, such as those incorporating Gymnema sylvestre, Momordica charantia, and Curcuma longa, demonstrate significant potential in improving glycemic control and mitigating diabetic complications through targeted delivery and sustained release. However, challenges related to standardization, scalability, and clinical validation persists, highlighting the need for rigorous research and collaborative efforts between traditional and modern scientific communities. The study concludes that Ayurvedic nanoformulations represent a viable complementary strategy for diabetes management, provided that further investigations address existing limitations and optimize their therapeutic potential. This review serves as a comprehensive resource for researchers and practitioners interested in the intersection of Ayurveda and nanotechnology for diabetes care.

Unmasking Warts: A Critical Review of Homoeopathic Research

Harpreet Kaur, Neha Pandey — Wed, 06 May 2026 01:23:53 +0530

Background: Warts are benign proliferations caused by human papilloma virus (HPV), affecting a substantial portion of the population and frequently resistant to conventional therapies. Homoeopathy has long been employed in their management. This review synthesizes clinical evidence from randomized controlled trials, observational studies, case series, and case reports on homoeopathic interventions for warts.

Materials and Methods: A structured search of published literature was undertaken. Thirteen studies met the criteria, including randomized controlled trials, observational studies, case series, and individual case reports. Data on study design, patient profile, remedies prescribed, potencies, treatment duration, outcome assessment, and follow-up were extracted and analyzed.

Results: Thirteen studies were reviewed. Early observational research documented high clearance rates with individualized prescriptions. A large randomized trial using a fixed combination of remedies found no difference compared to placebo, while a later pilot randomized trial employing individualized prescribing showed encouraging trends. Numerous case series and reports documented consistent and rapid resolution with individualized prescriptions such as Thuja, Causticum, Natrummuriaticum, Calcareaphosphorica, Medorrhinum, and others. Several recent cases employed MONARCH causality assessment, confirming definite or probable causal relationships. Reported treatment durations ranged from one to three months, with many studies noting absence of recurrence on long-term follow-up.

Conclusion: Homoeopathy appears promising in the management of warts, with encouraging results in observational and case-based literature. However, randomized controlled evidence remains limited and inconsistent. Larger multicenter trials using individualized prescribing and standardized outcome measures are essential to establish definitive efficacy.

MUCOADHESIVE POLYMER IN NOVEL DRUG DELIVERY: A PROMISING THERAPEUTIC STRATEGY

Basheera Bee Shek — Sun, 31 May 2026 00:00:00 +0530

Mucoadhesive drug delivery systems are designed to adhere to the mucosal surfaces of the body by interacting with the mucus layer and mucin glycoproteins, thereby enhancing the residence time of drug formulations at the site of absorption. This prolonged contact improves drug bioavailability, enables controlled and sustained drug release, and reduces dosing frequency, ultimately enhancing patient compliance. This review highlights the mechanisms and theories of cohesion, factors affecting mucoadhesive performance, types of mucoadhesive polymers, and recent developments, emphasizing their potential in targeted and patient-friendly drug delivery mucoadhesive systems have found wide applications in buccal, nasal, ocular, vaginal, and gastrointestinal drug delivery, particularly for peptides, proteins, and vaccines. This review highlights the mechanisms and theories of cohesion, factors affecting mucoadhesive performance, types of mucoadhesive polymers, and recent developments, emphasizing their potential in targeted and patient-friendly drug delivery system.

ADVANCEMENTS IN HEALTH THROUGH ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING

Khasim SK — Mon, 01 Jun 2026 00:00:00 +0530

The implementation of artificial intelligence (AI) is driving significant transformation inside the administrative and clinical workflows of healthcare organizations at an accelerated rate. This modification highlights the significant impact that AI has on a variety of tasks, especially in health procedures relating to early detection and diagnosis. Artificial Intelligence in healthcare helps to enhance patient diagnoses, improve prevention and treatment, increase cost efficiency, and serve as a way to provide equitable access and treatment for the entire role of artificial intelligence in the healthcare industry. On the positive side, artificial intelligence presents several opportunities in healthcare industry, including improved patient monitoring, managing patient data, predictive medicine; improved teamwork and decision-making, improved patient engagement and compliance; rehabilitation; and administrative applications. Ethical issues, such as data privacy and bias, are among the most significant challenges. While AI enhances efficiency and outcomes, human oversight remains essential to ensure safe, equitable, and ethical deployment. The future of healthcare will increasingly depend on responsible AI adoption that balances innovation with patient-centred values.