https://saapjournals.org/index.php/ijacm <p><strong>International Journal of Alternative and Complementary Medicine</strong></p> South Asian Academic Publication en-US International Journal of Alternative and Complementary Medicine 2583-1305 <p>Copyright © Author(s) retain the copyright of this article.</p> https://saapjournals.org/index.php/ijacm/article/view/744 <p>Early menopause, defined as the cessation of menstruation before the age of 45 years, affects up to 16.2% of Indian women and is linked to hormonal imbalance, musculoskeletal pain, psychological distress, and increased risk of osteoporosis and cardiovascular disease. Yoga has emerged as a potential non-pharmacological approach for managing menopausal symptoms. This case study evaluated the effectiveness of a structured yoga therapy protocol in managing hormonal imbalance and musculoskeletal pain in a 42-year-old woman experiencing early menopause. The patient underwent a six-month yoga therapy program consisting of 50-minute sessions, five days a week, with practices adapted from the “Yoga Protocol for Women of Reproductive Age” and modified during active menstruation. After six months, oestradiol levels increased by 25.41% while follicle-stimulating hormone levels decreased by 39.28%. Pain reduction was observed in multiple joints, including the lower back (75%), hip (44.4%), knee (37.5%), heel (44.4%), and shoulder (28.6%), though no improvement was noted in elbow pain and body mass index showed only minimal change (1.49%). These findings suggest yoga therapy may serve as a safe, effective, and cost-efficient intervention for early menopause management, particularly for improving hormonal balance and alleviating musculoskeletal discomfort. However, as this is a single case report without a control group, further research with larger, controlled trials is necessary to confirm these results.</p> Chaitanyaa Tripathi Bharathi Dhevi V R Krishna Dwivedi Copyright (c) 2025 Chaitanyaa Tripathi, Krishna Dwivedi https://creativecommons.org/licenses/by-nc/4.0 2025-11-30 2025-11-30 1 7 https://saapjournals.org/index.php/ijacm/article/view/777 <p style="text-align: justify; margin: 6.0pt 0in 6.0pt 0in;"><span lang="EN-GB" style="font-size: 11.0pt;">Homeopathy remains one of the most widely practiced complementary and alternative medicine (CAM) modalities worldwide, particularly among individuals with chronic non-communicable diseases (NCDs) who seek safe, holistic, and personalized therapeutic options. Despite its global popularity, controversy continues regarding its mechanisms of action and clinical effectiveness. This review critically evaluates the current evidence on the role of homeopathy in chronic disease management. A comprehensive review of randomized controlled trials (RCTs), systematic reviews, and meta-analyses published between 2000 and 2025 was conducted. Studies were included if they examined homeopathic interventions in chronic conditions such as asthma, arthritis, type 2 diabetes mellitus, depression, chronic pain, and fibromyalgia. Data were synthesized thematically to assess efficacy, mechanistic plausibility, methodological quality, and safety outcomes. Mechanistic hypotheses suggest that hormesis, nanoparticle-mediated signaling, immune modulation, and neuropsychological or psychosocial mechanisms may contribute to the therapeutic effects of homeopathy. Meta-analytic evidence demonstrates modest but statistically significant improvements in subjective measures such as pain, fatigue, and quality of life across several chronic diseases, with standardized mean differences ranging from 0.18 to 0.25. However, objective clinical outcomes, including spirometry and HbA1c, rarely show consistent benefit. Methodological challenges, including small sample sizes, heterogeneous interventions, limited follow-up durations, and a high risk of bias, continue to constrain the reliability of existing findings. Importantly, homeopathy exhibits a favorable safety profile, with no serious adverse events reported across chronic disease studies. Current evidence indicates that homeopathy may provide modest adjunctive benefits for symptom relief and improved patient satisfaction among individuals with chronic illnesses, although its specific therapeutic mechanisms remain uncertain. Integration of homeopathy into evidence-based, patient-centered chronic disease management frameworks may enhance holistic care. Future research should emphasize large-scale, multicenter randomized trials with standardized outcome measures and mechanistic endpoints to better define clinical relevance and biological plausibility.</span></p> Rani Sharkar Tithy Gaffar Miah Abdul Copyright (c) 2025 2025-11-30 2025-11-30