Appropriate Empirical Antibiotic Treatment and Vital Sign Outcome among Pneumonia Patients in Universitas Gadjah Mada Academic Hospital, Indonesia

Fivy Kurniawati; Nanang Munif Yasin; Luh Rai Maduretno Asvinigita; Elisabeth Vonni Hapsari

Fivy Kurniawati Pharmacology and Clinical Pharmacy Department, Faculty of Pharmacy, Universitas Gadjah Mada Yogyakarta, Indonesia
Nanang Munif Yasin1 Pharmacology and Clinical Pharmacy Department, Faculty of Pharmacy, Universitas Gadjah Mada Yogyakarta, Indonesia
Luh Rai Maduretno Asvinigita Pharmacy Graduated Student, Faculty of Pharmacy, Universitas Gadjah Mada Yogyakarta, Indonesia
Elisabeth Vonni Hapsari2 Pharmacy Graduated Student, Faculty of Pharmacy, Universitas Gadjah Mada Yogyakarta, Indonesia

Abstract

Pneumonia is defined as a common illness that remains to be the highest mortality rate in young children and the elderly-aged group in both of developed and developing countries. Pneumonia itself counted as the second out of the ten most common diseases from January to November 2018 inpatient care in the Universitas Gadjah Mada academic hospital. This study aimed to explore the appropriate of empirical antibiotics use based on Universitas Gadjah Mada Academic Hospital guideline of and to evaluate it’s vital sign outcome. This study used cross sectional method with retrospective data collection through patients’ medical report collected from January to June 2018 and driven descriptively. Specifically, the included patients in this study were hospitalized patients which diagnosed with pneumonia. Overall, there are total of 197 patients with Pneumonia or Bronchopneumonia diagnosed which particularly consisted of 98 children’s patients and 97 adults. The highest prevalence of antibiotic treatment in academic hospital were using empirical antibiotic which is betalactam-penicilin antibiotic group for children patients and betalactam-cephalosporin antibiotic group for adult patients diagnosed with pneumonia. Moreover, the abnormality of patient’s vital signs after the 48 until 72 hours duration of treatment were decrease remarkably. Regarding to the appropriate use of empirical antibiotic treatment which observed in children was reported low roughly around 0.071%, meanwhile in adults almost a half of observed patients were appropriated. Through this pioneer study the hospital’s guideline on local pneumonia treatment should re-evaluate in order to improve the appropriate empirical usage of antibiotics.

Keywords: pneumonia, local hospital giudeline, appropriate empirical use of antibiotics, Universitas Gadjah Mada Academic Hospital

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