AN INSIGHT INTO MOTHER NATURE’S MIRACLE PLANT - KALANCHOE PINNATA
Miracle Plant - Kalanchoe Pinnata
Abstract
Kalanchoe pinnata, a perennial succulent plant inhabiting warm tropical climates, is a popular house plant with innumerable medicinal properties. This review gives an insight on the chemical constituents of the plant, medicinal properties and uses. The various clinical applications of the plant have been discussed in detail with focus on its anti cancer effects.
Keywords:
Kalanchoe pinnata, Bryophyllum calycinum, miracle leaf, Medicinal uses
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References
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11. Gaind K, Gupta R. Identification of waxes from leaves of Kalanchoe pinnata. Planta Med. 1974;23:193-7.
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14. Rastogi RP, Mehrotra BN. Compendium of Indian Medicinal Plants. Vol. 5. New Delhi: PID; 1990-1994. p. 141-3.
15. Yadav NP, Dixit VK. Hepatoprotective activity of leaves of Kalanchoe pinnata Pers. J Ethnopharmacol. 2003;86:197-202.
16. Biswas SK, Chowdhury A, Das J, Hosen SZ, Uddin R, Rahaman MS. Literature review on pharmacological potentials of Kalanchoe pinnata (Crassulaceae). Afr J Pharm Pharmacol. 2011;5:1258-62.
17. Dalziel JM. The Useful Plants of West Tropical Africa. London: Crown Agents for the Colonies; 1937.
18. Rajsekhar P, Bharani RA, Ramachandran M, Angel KJ, Rajsekhar SPV. The “wonder plant” Kalanchoe pinnata (Linn.) Pers.: a review. J Appl Pharm Sci. 2016;6:151-8.
19. Sharker SM, Hossain MK, Haque MR, Chowdhury AA, Kaisar A, Hasan CM, et al. Chemical and biological studies of Kalanchoe pinnata (Lam.) growing in Bangladesh. Asian Pac J Trop Biomed. 2012;2:S1317-S1322.
20. Akinpelu DA. Antimicrobial activity of Bryophyllum pinnatum leaves. Fitoterapia. 2000;71:193-4.
21. Kamboj A, Saluja AK. Bryophyllum pinnatum (Lam.) Kurz.: phytochemical and pharmacological profile: a review. Pharmacogn Rev. 2009;3:364.
22. Supratman U, Fujita T, Akiyama K, Hayashi H, Murakami A, Sakai H, et al. Anti-tumour promoting activity of bufadienolides from Kalanchoe pinnata and K. daigremontiana × tubiflora. Biosci Biotechnol Biochem. 2001;65:947-9.
23. Parez AC, Correa MF, Borges SR. Antiulcer activity from leaves of Bryophyllum spp. Arch Vet Sci. 1999;4:111-2.
24. Ogbonnia SO, Odimegwu JI, Enwuru VN. Evaluation of hypoglycemic and hypolipidemic effects of aqueous ethanolic extracts of Treculia africana and Bryophyllum pinnatum and their mixtures on streptozotocin-induced diabetic rats. Afr J Biotechnol. 2008;7:2535-9.
25. Akinpelu DA. Antimicrobial activity of Bryophyllum pinnatum leaves. Fitoterapia. 2000;71:193-4.
26. Mahamood K, Patil PK. Influence of Bryophyllum pinnatum leaf extract on wound healing in albino rats. Indian J Pharmacol. 2002;34:151-2.
27. Kalita K, Kashyap B, Ahmed R, Sarma H, Dutta KN, Deka K, et al. Distribution, ethnomedicinal uses, phytochemical profile and pharmacological activities of Kalanchoe pinnata (Lam.) Pers.: a review. J Bioresour. 2022;9:1-6.
28. Pattewar SV. Kalanchoe pinnata: phytochemical and pharmacological profile. Int J Phytopharm. 2012;2:1-8.
29. Rocha LG, Almeida JRGS, Macedo RO, Barbosa-Filho JM. A review of natural products with antileishmanial activity. Phytomedicine. 2005;12:514-35.
30. Muzitano MF, Luzineide WT, Catherine G, Kaiser CR, Ross-Bergmann B, Costa SS. The antileishmanial activity assessment of unusual flavonoids from Kalanchoe pinnata. Phytochemistry. 2006;67:2071-7.
2. Mandal S, Ghosh S, Dey S, Sarkar T. A traditional life plant Kalanchoe pinnata: phytochemical and pharmacological studies. Int J Multidiscip Res (IJFMR). 2024;6.
3. Rahman R, Al-Sabahi JN, Ghaffar A, Umar FN. Phytochemical, morphological, botanical and pharmacological aspects of a medicinal plant: Kalanchoe pinnata – a review article. Int J Chem Biochem Sci. 2019;16:5-10.
4. Biswas SK, Chowdhury A, Das J, Hosen SMZ, Uddin R, Rahaman MS. A review of the traditional medicinal uses of Kalanchoe pinnata (Crassulaceae). Int J Pharm Pharmacol. 2021;10:1-5.
5. Tajudin NJ, Ismail INA. Antimicrobial activity of Kalanchoe pinnata: a review. Malays J Sustain Health Technol. 2021;8:31-37.
6. Rahman R, Al-Sabahi JN, Ghaffar A, Umar FN. Phytochemical, morphological, botanical and pharmacological aspects of a medicinal plant: Kalanchoe pinnata – a review article. Int J Chem Biochem Sci. 2019;16:5-10.
7. Singh RK, Garg A, Shrimali K. Botanical description, phytochemistry, traditional uses, and pharmacology of the “wonder plant” Kalanchoe pinnata (Linn.) Pers: an updated review. J Pharm Med Chem. 2022;8:11-24.
8. Mahata S, et al. Anticancer property of Bryophyllum pinnata (Lam.) Oken leaf on human cervical cancer cells. BMC Complement Altern Med. 2012;12:15.
9. Marriage PB, Wilson DG. Analysis of organic acids of Bryophyllum pinnatum. Can J Biochem. 1971;49:282-95.
10. Gaind K, Gupta R. Alkanes, alkanols, triterpenes, and sterols of Kalanchoe pinnata. Phytochemistry. 1972;11:1500-2.
11. Gaind K, Gupta R. Identification of waxes from leaves of Kalanchoe pinnata. Planta Med. 1974;23:193-7.
12. McKenzie RA, Franke FP, Dunster PJ. The toxicity to cattle and bufadienolide content of six Bryophyllum species. Aust Vet J. 1987;64:298-301.
13. Yamagishi T, Haruna M, Yan XZ, Chang JJ, Lee KH. Antitumor agents. 110. Bryophyllin B, a novel potent cytotoxic bufadienolide from Bryophyllum pinnatum. J Nat Prod. 1989;52:1071-9.
14. Rastogi RP, Mehrotra BN. Compendium of Indian Medicinal Plants. Vol. 5. New Delhi: PID; 1990-1994. p. 141-3.
15. Yadav NP, Dixit VK. Hepatoprotective activity of leaves of Kalanchoe pinnata Pers. J Ethnopharmacol. 2003;86:197-202.
16. Biswas SK, Chowdhury A, Das J, Hosen SZ, Uddin R, Rahaman MS. Literature review on pharmacological potentials of Kalanchoe pinnata (Crassulaceae). Afr J Pharm Pharmacol. 2011;5:1258-62.
17. Dalziel JM. The Useful Plants of West Tropical Africa. London: Crown Agents for the Colonies; 1937.
18. Rajsekhar P, Bharani RA, Ramachandran M, Angel KJ, Rajsekhar SPV. The “wonder plant” Kalanchoe pinnata (Linn.) Pers.: a review. J Appl Pharm Sci. 2016;6:151-8.
19. Sharker SM, Hossain MK, Haque MR, Chowdhury AA, Kaisar A, Hasan CM, et al. Chemical and biological studies of Kalanchoe pinnata (Lam.) growing in Bangladesh. Asian Pac J Trop Biomed. 2012;2:S1317-S1322.
20. Akinpelu DA. Antimicrobial activity of Bryophyllum pinnatum leaves. Fitoterapia. 2000;71:193-4.
21. Kamboj A, Saluja AK. Bryophyllum pinnatum (Lam.) Kurz.: phytochemical and pharmacological profile: a review. Pharmacogn Rev. 2009;3:364.
22. Supratman U, Fujita T, Akiyama K, Hayashi H, Murakami A, Sakai H, et al. Anti-tumour promoting activity of bufadienolides from Kalanchoe pinnata and K. daigremontiana × tubiflora. Biosci Biotechnol Biochem. 2001;65:947-9.
23. Parez AC, Correa MF, Borges SR. Antiulcer activity from leaves of Bryophyllum spp. Arch Vet Sci. 1999;4:111-2.
24. Ogbonnia SO, Odimegwu JI, Enwuru VN. Evaluation of hypoglycemic and hypolipidemic effects of aqueous ethanolic extracts of Treculia africana and Bryophyllum pinnatum and their mixtures on streptozotocin-induced diabetic rats. Afr J Biotechnol. 2008;7:2535-9.
25. Akinpelu DA. Antimicrobial activity of Bryophyllum pinnatum leaves. Fitoterapia. 2000;71:193-4.
26. Mahamood K, Patil PK. Influence of Bryophyllum pinnatum leaf extract on wound healing in albino rats. Indian J Pharmacol. 2002;34:151-2.
27. Kalita K, Kashyap B, Ahmed R, Sarma H, Dutta KN, Deka K, et al. Distribution, ethnomedicinal uses, phytochemical profile and pharmacological activities of Kalanchoe pinnata (Lam.) Pers.: a review. J Bioresour. 2022;9:1-6.
28. Pattewar SV. Kalanchoe pinnata: phytochemical and pharmacological profile. Int J Phytopharm. 2012;2:1-8.
29. Rocha LG, Almeida JRGS, Macedo RO, Barbosa-Filho JM. A review of natural products with antileishmanial activity. Phytomedicine. 2005;12:514-35.
30. Muzitano MF, Luzineide WT, Catherine G, Kaiser CR, Ross-Bergmann B, Costa SS. The antileishmanial activity assessment of unusual flavonoids from Kalanchoe pinnata. Phytochemistry. 2006;67:2071-7.
Published
20/05/2026
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C. N, N. S, and V. N, “AN INSIGHT INTO MOTHER NATURE’S MIRACLE PLANT - KALANCHOE PINNATA: Miracle Plant - Kalanchoe Pinnata”, Int J Indig Herb Drug, vol. 11, no. 1, pp. 31-34, May 2026.
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