Assessment of antimicrobial use in private and government hospitals, a comparative study in central kerala, using who indicators

Chinnu Roy; Shaji George; Aleena Issac; Arya Ponnappan; Dhanya Paul

doi:10.46956/ijihd.v6i4.236

Chinnu Roy Pharm. D Intern. Nirmala College of Pharmacy, Muvattupuzha, Kerala-686661
Shaji George Professor & Head, Department of Pharmacy Practice, Nirmala College of Pharmacy, Muvattupuzha, Kerala-686661
Aleena Issac Pharm. D Intern. Nirmala College of Pharmacy, Muvattupuzha, Kerala-686661
Arya Ponnappan Pharm. D Intern. Nirmala College of Pharmacy, Muvattupuzha, Kerala-686661
Dhanya Paul Pharm. D Intern. Nirmala College of Pharmacy, Muvattupuzha, Kerala-686661

DOI https://doi.org/10.46956/ijihd.v6i4.236

Abstract

Background: Irrational use of antimicrobial can cause various unwanted and untoward events. It may diminish the quality of patient care, increase the cost of therapy, and involvement in various side effects. Thus, the appropriateness of antimicrobial use in hospitals plays a pivotal role in patient safety.

Objective: To analyze and assess the prescribing pattern of antimicrobials in private and government hospitals as per the WHO indicators.

Methodology: A prospective comparative observational study was carried out for 6 months, with the patient diagnosed with an infectious disease admitted to the medical ward of both the hospitals during the study period. The data obtained from the study sites were Compared and analyzed using WHO indicators described in WHO’s “How to Investigate Antimicrobial use in Hospitals: Selected Indicators, Feb 2012”.

Results: The study involved 216 patients and the average number of antimicrobials prescribed was found to be 1.73 in a private hospital and 2.07 in the government hospital, average cost of antimicrobials was found to be 86.48 INR in private and 31.04 INR in the government hospital, average duration of antimicrobial treatment was 4.8 in private and 5.2 in the government hospital, and the percentage of antimicrobials prescribed in generic was 33.33% in private and 87.83% in the government hospital. Considering the spectrum of antibiotics, both private (94.7%) and government (88.8%) used broad-spectrum antimicrobials. In both hospitals, cephalosporins were the most frequently prescribed class of antimicrobials. Comparing the dosage of antimicrobials given, injection usage is at the highest in government (59.5%) as well as in the private hospital (68.4%).

Conclusion: This study indicates that the average cost of antimicrobials was more in a private hospital than that in a government hospital and other indicators such as the number of antimicrobials per hospitalization, duration of antimicrobial treatment, and the percentage of generic antimicrobials prescribed were all found to be more in a government hospital. In both private and government hospitals broad-spectrum antimicrobials were widely used, with cephalosporin as the most prescribed class.

Keywords: Antimicrobials, private hospital, Government hospital, WHO indicators, Broad spectrum, Generic antimicrobials

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